Evidence map›Paper›PMID 39189613›Full record

ArticleJournal of the American Heart Association2024

Trends in Complications Among Patients Undergoing Aortic Valve Replacement in the United States.

James E Harvey, Samir R Kapadia, David J Cohen, Ankur Kalra, William Irish, Candace Gunnarsson, Michael Ryan, Soumya G Chikermane, Christin Thompson, Rishi Puri

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Same-Day Discharge After Transcatheter Aortic Valve Implantation: Who, When, and How?Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. A Narrative Review of the Evidence for Transcatheter Aortic Valve Implants.Journal of cardiovascular development and disease · 2025
    Review
  11. Review
  12. Article
  13. Paradigm Shift in the Management of Aortic Stenosis.Journal of the American Heart Association · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

James E HarveyWellSpan Health System York PA USA.ORCID 0000-0002-6656-375X
Samir R KapadiaDepartment of Cardiovascular Medicine Cleveland Clinic Cleveland OH USA.ORCID 0000-0002-0026-3391
David J CohenCardiovascular Research Foundation and St Francis Hospital Roslyn NY USA.ORCID 0000-0001-9163-724X
Ankur KalraFranciscan Health Lafayette IN USA.ORCID 0000-0003-0080-1660
William IrishBrody School of Medicine Greenville NC USA.ORCID 0000-0003-2605-5950
Candace GunnarssonGunnarsson Consulting Jupiter FL USA.ORCID 0000-0003-0723-585X
Michael RyanMPR Consulting Cincinnati OH USA.ORCID 0000-0002-7207-7926
Soumya G ChikermaneEdwards Lifesciences Irvine CA USA.ORCID 0000-0001-5335-3430
Christin ThompsonEdwards Lifesciences Irvine CA USA.ORCID 0000-0002-4713-4730
Rishi PuriDepartment of Cardiovascular Medicine Cleveland Clinic Cleveland OH USA.ORCID 0000-0001-8849-7426

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe treatment of severe aortic stenosis has evolved considerably since the introduction of transcatheter aortic valve replacement (TAVR), yet trends in complications for patients undergoing TAVR or surgical aortic valve replacement (SAVR) at a national level have yet to be evaluated. METHODS AND

resultsWe performed a retrospective cohort study using Medicare data to evaluate temporal trends in complications among beneficiaries, aged ≥65 years, treated with elective isolated transfemoral TAVR or SAVR between 2012 and 2019. The study end point was the occurrence of a major complication (composite outcome) during index and up to 30 days after. Multivariable logistic regression was used to assess odds of complications for TAVR and SAVR, individually over time, and for TAVR versus SAVR, over time. The cohort included 211 212 patients (mean±SD age, 78.6±7.3 years; 45.0% women). Complication rates during index following elective isolated aortic valve replacement decreased from 49% in 2012 to 22% in 2019. These reductions were more pronounced for TAVR (41% to >19%, Δ=22%) than SAVR (51% to >47%, Δ=4%). After risk adjustment, the risk of any complication with TAVR was 47% (

conclusionsBetween 2012 and 2019, the risk of complications after aortic valve replacement among Medicare beneficiaries decreased significantly, with larger absolute and relative changes among patients treated with TAVR than SAVR.

Indexed as

Aortic Valve StenosisPostoperative ComplicationsTranscatheter Aortic Valve ReplacementAgedAged, 80 and overAortic ValveFemaleHeart Valve Prosthesis ImplantationHumansMaleMedicareRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment Outcomeaortic stenosiscomplicationssurgical aortic valve replacementtranscatheter aortic valve replacementtrends

Identifiers

PMID39189613
PMCPMC11646526

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.