Evidence map›Paper›PMID 39189285›Full record

ReviewPediatric reports2024

Acquired and Inherited Zinc Deficiency-Related Diseases in Children: A Case Series and a Narrative Review.

Tommaso Bellini, Marta Bustaffa, Barbara Tubino, Benedetta Giordano, Clelia Formigoni, Elena Fueri, Federica Casabona, Barbara Vanorio, Andrea Pastorino, Astrid Herzum and 4 more

Abstract readReview
In one paragraph

Review in Pediatric reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Case Report: Identification of aFrontiers in genetics · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Tommaso BelliniPediatric Emergency Room and Emergency Medicine Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.ORCID 0000-0001-7559-0111
Marta BustaffaPediatric Emergency Room and Emergency Medicine Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.
Barbara TubinoPediatric Emergency Room and Emergency Medicine Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.
Benedetta GiordanoDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal, and Child Health (DINOGMI), University of Genoa, 16132 Genoa, Italy.
Clelia FormigoniDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal, and Child Health (DINOGMI), University of Genoa, 16132 Genoa, Italy.
Elena FueriDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal, and Child Health (DINOGMI), University of Genoa, 16132 Genoa, Italy.
Federica CasabonaDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal, and Child Health (DINOGMI), University of Genoa, 16132 Genoa, Italy.
Barbara VanorioDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal, and Child Health (DINOGMI), University of Genoa, 16132 Genoa, Italy.
Andrea PastorinoDepartment of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal, and Child Health (DINOGMI), University of Genoa, 16132 Genoa, Italy.
Astrid HerzumDermatology Unit, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.
Caterina Matucci-CerinicReumatology and Autoinflammatory Diseases Unit, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.ORCID 0000-0003-3710-0569
Serena ArrigoGastroenterology and Digestive Endoscopy Unit, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.
Gianmaria ViglizzoDermatology Unit, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.
Emanuela PiccottiPediatric Emergency Room and Emergency Medicine Unit, Emergency Department, IRCCS Istituto Giannina Gaslini, 16147 Genoa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Zinc deficiency is a significant global health concern among children, manifesting in various acquired and inherited conditions. This comprehensive overview of acquired and inherited zinc deficiency-related diseases in children aimed to explore the clinical presentations, diagnostic challenges, and management strategies associated with these conditions. This case series elucidates the diverse clinical manifestations of zinc deficiency in pediatric patients, ranging from dermatitis and growth retardation to immune dysregulation and neurological abnormalities, and discusses the underlying genetic mechanisms, clinical phenotypes, and therapeutic interventions. The complexity of zinc deficiency-related diseases in children underscores the need for a multidisciplinary approach involving pediatricians, dermatologists, geneticists, and nutritionists to optimize patient care and outcomes.

Indexed as

acquired zinc deficiencyacrodermatitis enteropathicadermatitismetabolic diseasespediatric emergency departmentstransient neonatal zinc deficiency

Identifiers

PMID39189285
PMCPMC11348185

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.