Evidence map›Paper›PMID 39189261›Full record

ArticleJournal of developmental biology2024

Lowered GnT-I Activity Decreases Complex-Type N-Glycan Amounts and Results in an Aberrant Primary Motor Neuron Structure in the Spinal Cord.

Cody J Hatchett, M Kristen Hall, Abel R Messer, Ruth A Schwalbe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of developmental biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Cody J HatchettDepartment of Biochemistry and Molecular Biology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.ORCID 0000-0002-4595-3425
M Kristen HallDepartment of Biochemistry and Molecular Biology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.ORCID 0009-0009-4065-7369
Abel R MesserDepartment of Biochemistry and Molecular Biology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.
Ruth A SchwalbeDepartment of Biochemistry and Molecular Biology, Brody School of Medicine, East Carolina University, Greenville, NC 27834, USA.ORCID 0000-0002-6839-7863

Funding

Roles of N-glycans on potassium channel functionR15GM129679 · NIGMS · EAST CAROLINA UNIVERSITY · PI SCHWALBE, RUTH A · 2018 to 2018
$438k
National Institute of Health R15GM129679NIGMS NIH HHS R15 GM129679Wooten Family Initiative for Brain Health Research RAS
6 · The paper itself

Abstract

The attachment of sugar to proteins and lipids is a basic modification needed for organismal survival, and perturbations in glycosylation cause severe developmental and neurological difficulties. Here, we investigated the neurological consequences of N-glycan populations in the spinal cord of Wt AB and

Indexed as

developmentglycomicsmotor neuronsN-acetylglucosaminyltransferase-I (GnT-I)N-glycansoligomannosespinal cord

Identifiers

PMID39189261
PMCPMC11348029

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.