Evidence map›Paper›PMID 39189199›Full record

ArticleMedical sciences (Basel, Switzerland)2024

Prognostic Role of Pre- and Post-Treatment [18F]FDG PET/CT in Squamous Cell Carcinoma of the Oropharynx in Patients Treated with Chemotherapy and Radiotherapy.

Francesco Dondi, Maria Gazzilli, Domenico Albano, Alessio Rizzo, Giorgio Treglia, Antonio Rosario Pisani, Carmen Palumbo, Dino Rubini, Manuela Racca, Giuseppe Rubini and 1 more

Abstract read
In one paragraph

Article in Medical sciences (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Francesco DondiNuclear Medicine, Università degli Studi di Brescia and ASST Spedali Civili di Brescia, 25123 Brescia, Italy.ORCID 0000-0003-4839-9033
Maria GazzilliNuclear Medicine, ASL Bari-P.O. Di Venere, 70012 Bari, Italy.ORCID 0000-0001-8289-2054
Domenico AlbanoNuclear Medicine, Università degli Studi di Brescia and ASST Spedali Civili di Brescia, 25123 Brescia, Italy.ORCID 0000-0003-0810-6494
Alessio RizzoDepartment of Nuclear Medicine, Candiolo Cancer Institute, FPO-IRCCS, 10060 Turin, Italy.ORCID 0009-0007-5438-8230
Giorgio TregliaClinic of Nuclear Medicine, Imaging Institute of Southern Switzerland, Ente Ospedaliero Cantonale, 6501 Bellinzona, Switzerland.ORCID 0000-0001-9808-780X
Antonio Rosario PisaniNuclear Medicine Section, Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0002-3335-9541
Carmen PalumboNuclear Medicine Section, Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.
Dino RubiniDepartment of Precision Medicine, University of Campania "L. Vanvitelli", 80138 Naples, Italy.ORCID 0000-0003-3807-0752
Manuela RaccaDepartment of Nuclear Medicine, Candiolo Cancer Institute, FPO-IRCCS, 10060 Turin, Italy.ORCID 0000-0002-9350-1239
Giuseppe RubiniNuclear Medicine Section, Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", 70124 Bari, Italy.ORCID 0000-0003-1972-3308
Francesco BertagnaNuclear Medicine, Università degli Studi di Brescia and ASST Spedali Civili di Brescia, 25123 Brescia, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe prognostic role of imaging with [18F]fluorodeoxyglucose ([18F]FDG) positron emission tomography/computed tomography (PET/CT) in oropharynx cancer (OPC) has been demonstrated in the past. The aim of this study was to assess the prognostic impact of both baseline and post-treatment PET/CT in patients with OPC and treated with chemo- and/or radiotherapy.

methodsThe PET/CT parameters of scans performed before and after therapy were collected and analyzed to find significant prognosticators for progression-free survival (PFS) and overall survival (OS). Human papillomavirus (HPV) infection's influence on the prognosis was also taken into account.

resultsA total of 66 patients were included in the study. The staging volumetric parameters of PET/CT were significant prognosticators for OS, while the same parameters were affordable predictors for PFS at the restaging evaluation. No significant correlations between HPV infection and PET/CT parameters were reported.

conclusionThe prognostic role of volumetric [18F]FDG PET/CT parameters in patients with OPC was reported.

Indexed as

Fluorodeoxyglucose F18Oropharyngeal NeoplasmsPositron Emission Tomography Computed TomographyAdultAgedAged, 80 and overCarcinoma, Squamous CellChemoradiotherapyFemaleHumansMaleMiddle AgedPapillomavirus InfectionsPrognosisRadiopharmaceuticalsRetrospective StudiesFluorodeoxyglucose F18Radiopharmaceuticals[18]F-FDGhead and neckHPVoropharynxPET/CTpositron emission tomographySCCsquamous cell carcinoma

Identifiers

PMID39189199
PMCPMC11348019

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.