Evidence map›Paper›PMID 39189174›Full record

ArticleJournal of xenobiotics2024

Association between Liver and Kidney Function and Birth Outcomes in Pregnant Surinamese Women Exposed to Mercury and Lead in the Caribbean Consortium for Research in Environmental and Occupational Health (CCREOH) Environmental Epidemiologic Cohort Study.

Sheila Kort, Jeffrey Wickliffe, Arti Shankar, Hannah H Covert, Maureen Lichtveld, Wilco Zijlmans

Abstract read
In one paragraph

Article in Journal of xenobiotics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Mercury Exposure and Health Effects: What Do We Really Know?International journal of molecular sciences · 2025
    Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sheila KortFaculty of Medical Sciences, Anton de Kom University of Suriname, P.O. Box 9212 Paramaribo, Suriname.ORCID 0000-0003-1449-8025
Jeffrey WickliffeDepartment of Environmental Health Sciences, School of Public Health, University of Alabama at Birmingham, Birmingham, AL 35294, USA.ORCID 0000-0002-6216-9894
Arti ShankarDepartment of Biostatistics and Data Science, School of Public Health and Tropical Medicine, Tulane University, New Orleans, LA 70112, USA.
Hannah H CovertDepartment of Environmental and Occupational Health, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID 0000-0001-9483-8557
Maureen LichtveldDepartment of Environmental and Occupational Health, School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Wilco ZijlmansFaculty of Medical Sciences, Anton de Kom University of Suriname, P.O. Box 9212 Paramaribo, Suriname.ORCID 0000-0002-4080-3858

Funding

1/2-Neurotoxicant exposures:impact maternal and child health in Suriname-SurinameU01TW010087 · FIC · ACADEMISCH ZIEKENHUIS PARAMARIBO · PI LICHTVELD, MAUREEN Y., MANS, DENNIS R.A. · 2015 to 2020
$1.9M
2/2-Neurotoxicant Exposures: Impact on Maternal and Child Health in Suriname-USU2RTW010104 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI LICHTVELD, MAUREEN Y., MANS, DENNIS R.A. · 2015 to 2020
$1.5M
FIC NIH HHS U01 TW010087FIC NIH HHS U2R TW010104Fogarty International Center of the National Institutes of Health U01TW010087-01 and U2RTW010104
6 · The paper itself

Abstract

Exposure to mercury (Hg) and lead (Pb), in combination with liver and kidney impairment, may result in adverse birth outcomes. From 408 women in the age range of 16 to 46 years, living in rural and urban areas in the interior of Suriname, we looked at the association between adverse birth outcomes and exposure to Hg and Pb in combination with liver and kidney function. This group of women represented a subcohort of pregnant women who participated in the Caribbean Consortium for Research in Environmental and Occupational Health (CCREOH)-Meki Tamara study. Liver function was assessed by measuring aspartate amino transferase (AST), alanine amino transferase (ALT), and gamma-glutamyl transferase (GGT). Kidney function was assessed by measuring creatinine, urea, and cystatin C. We defined preterm births as birth before 37 weeks of gestation, low birthweight as birthweight < 2500 g, and low Apgar score as a score < 7 at 5 min, and these were used as indicators for adverse birth outcomes. Small size for gestational age was defined as gestational age < -2SD weight for GA. We found significant statistical associations between biomarkers for liver and kidney functions and adverse birth outcomes Apgar score and gestational age. No significant association was found between heavy metals Hg and lead and adverse birth outcomes.

Indexed as

apgar scorebirthweightgestational ageheavy metalskidney functionliver functionpregnant women

Identifiers

PMID39189174
PMCPMC11348017

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.