Evidence map›Paper›PMID 39188890›Full record

ArticleResearch and practice in thrombosis and haemostasis2024

The association between unemployment and treatment among adults with hemophilia.

Christian Qvigstad, Lars Q Sørensen, Geir E Tjønnfjord, Pål André Holme, Age-related DeVelopments ANd ComorbiditiEs in hemophilia Working Group

Abstract read
In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Christian QvigstadDepartment of Haematology, Oslo University Hospital Rikshospitalet, Rikshospitalet, Norway.
Lars Q SørensenIndependent researcher, Oslo, Norway.
Geir E TjønnfjordDepartment of Haematology, Oslo University Hospital Rikshospitalet, Rikshospitalet, Norway.
Pål André HolmeDepartment of Haematology, Oslo University Hospital Rikshospitalet, Rikshospitalet, Norway.
Age-related DeVelopments ANd ComorbiditiEs in hemophilia Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: People with hemophilia often experience pain and suffer from comorbidities related to their bleeding disorder. Consequently, unemployment due to disability is prevalent among people with hemophilia. Objectives: To explore associations between unemployment due to disability and treatment while adjusting for known risk factors for unemployment. Methods: Collecting data from 20 hemophilia centers from 15 European countries, the Age-related DeVelopments ANd ComorbiditiEs in hemophilia study recruited 785 participants aged 40 years and over with hemophilia A or B. A comprehensive electronic case report form included items related to patient characteristics, demographic information, past and current treatment regimens, and medical history, including a lifelong history of comorbidities. Baseline data from the Age-related DeVelopments ANd ComorbiditiEs in hemophilia study was analyzed using descriptive statistics and logistic regression models. Results: Employment status was available for 756 of 785 participants aged 40 to 88 years (median, 53 years). We used regression analysis to compare people with hemophilia who were fully employed with those who were unemployed due to disability. This analysis included 424 participants. Using multivariable logistic regression, we found that age (odds ratio [OR], 1.07; Conclusion: Our analysis suggests that by maintaining factor levels above a critical threshold (3%-5%), prophylactic treatment for people with hemophilia could help avoid unemployment due to disability. While prophylaxis is more costly and can be burdensome, the benefits to material well-being and quality of life could be substantial.

Indexed as

hemophilia Ahemophilia Btreatmentunemploymentworkforce

Identifiers

PMID39188890
PMCPMC11345527

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.