Investigating salivary matrix metalloproteinase-2 and matrix metalloproteinase-9 activity in fixed orthodontic-induced gingival enlargement.

Narges Ziaei, Amir Kiani, Ehsan Mohammadi-Noori, Shahram Arishi, Shima Golmohammadi

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In one paragraph

Article in Dental research journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Gingival Enlargement Induced by Orthodontic Therapy: A Systematic Review.International journal of dentistry · 2026
Review

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5 · Who and what money

Authors and funding

5 authors.

Narges ZiaeiDepartments of Periodontics, Dental School, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Amir KianiRegenerative Medicine Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Ehsan Mohammadi-NooriPharmaceutical Sciences Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Shahram ArishiDepartments of Periodontics, Dental School, Kermanshah University of Medical Sciences, Kermanshah, Iran.

Shima GolmohammadiDepartment of Periodontics, Dental School, Islamic Azad University, Borujerd, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Gingival enlargement (GE) is a common clinical observation among orthodontic patients, yet its underlying causes remain unclear. This study aims to investigate the potential involvement of salivary matrix metalloproteinase (MMP)-2 and MMP-9 activity in orthodontic-induced GE. Materials and Methods: In this case-control study, we enrolled 50 subjects, including 25 individuals with GE and 25 without. The participants, aged 10-35 years, were in the 4 Results: MMP-2 activity was undetectable in the zymograms. In the 4 Conclusion: The activity of MMP-9 in the saliva of orthodontic patients with GE increases during the 4

Indexed as

Fixed orthodontic appliancesgingival overgrowthmatrix metalloproteinase-2matrix metalloproteinase-9

Identifiers

PMID39188395

PMCPMC11346616

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.