Evidence map›Paper›PMID 39188263›Full record

ArticleActa naturae

Ceramides As Potential New Predictors of the Severity of Acute Coronary Syndrome in Conjunction with SARS-CoV-2 Infection.

N G Lozhkina, O I Gushchina, N V Basov, E V Gaisler, A D Rogachev, Yu S Sotnikova, Yu V Patrushev, A G Pokrovsky

Abstract read
In one paragraph

Article in Acta naturae. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

N G LozhkinaNovosibirsk State University, Novosibirsk, 630090 Russian Federation.
O I GushchinaFederal Research Center for Fundamental and Translational Medicine, Novosibirsk, 630117 Russian Federation.
N V BasovNovosibirsk State University, Novosibirsk, 630090 Russian Federation.
E V GaislerNovosibirsk State University, Novosibirsk, 630090 Russian Federation.
A D RogachevNovosibirsk State University, Novosibirsk, 630090 Russian Federation.
Yu S SotnikovaNovosibirsk State University, Novosibirsk, 630090 Russian Federation.
Yu V PatrushevNovosibirsk State University, Novosibirsk, 630090 Russian Federation.
A G PokrovskyNovosibirsk State University, Novosibirsk, 630090 Russian Federation.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute coronary events (ACEs) associated with a SARS-CoV-2 infection can significantly differ from classic ACEs. New biomarkers, such as ceramides, may help in the diagnosis and treatment of this disease. This study included 73 ACE patients for whom the SARS-CoV-2 infection was verified. Two subgroups were formed: the favorable outcome subgroup and the fatal outcome subgroup. Plasma samples were collected from all patients at the time of admission for a metabolomic analysis. The analysis of metabolites revealed that the ceramide levels were significantly lower in the fatal outcome subgroup than in the survivor subgroup. Therefore, determining ceramide levels in patients with ACEs in conjunction with COVID-19 may help assess the prognosis of these patients and manage their risks.

Indexed as

acute coronary syndromeceramidesmetabolomicsmyocardial infarctionSARS-CoV-2 infection

Identifiers

PMID39188263
PMCPMC11345093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.