Evidence map›Paper›PMID 39187976›Full record

ArticleOrthopaedic surgery2024

Analysis of Failed Atlantoaxial Reduction: Causes of Failure and Strategies for Revision.

Boyan Zhang, Yueqi Du, Can Zhang, Maoyang Qi, Hongfeng Meng, Tianyu Jin, Guoqing Cui, Jian Guan, Wanru Duan, Zan Chen

Abstract read
In one paragraph

Article in Orthopaedic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Boyan Zhang *Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-8407-5637
Yueqi Du *Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0009-0009-8604-4955
Can ZhangDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-9191-3328
Maoyang QiDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0009-0000-8971-666X
Hongfeng MengDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0009-0003-6791-5838
Tianyu JinDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0003-0760-2904
Guoqing CuiDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0009-0003-7878-7499
Jian GuanDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0009-0005-7244-9119
Wanru DuanDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0003-4751-3666
Zan ChenDepartment of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.ORCID https://orcid.org/0000-0002-0104-115X

Funding

Beijing Hospitals Authority Clinical medicine Development of special funding support XMLX202138Beijing Municipal Hospital Administration QML20210801Beijing Municipal Science & Technology Commission Z221100007422019Beijing Natural Science Foundation Grant L212039National High Level Hospital Clinical Research Funding 2022-PUMCH-D-004National Key R&D Program of China, "Research on Prevention and Control of Common Diseases", Supported by Ministry of Science & Technology of PRC 2023YFC2509700The CAMS Innovation Fund for Medical Sciences CIFMS#2021-1-I2M-025
6 · The paper itself

Abstract

objectiveThe craniovertebral junction (CVJ) presents intricate anatomical challenges. In severe or irreducible malformations, complications such as reduction loss and fixation failure may occur, necessitating revision surgery. The posterior facet joint distraction and fusion (PFDF) technique, offers a solely posterior approach for revisions. Hence, we delineate varied revision scenarios, proposing surgical strategies and technical details to enhance outcomes and mitigate risks, thereby enriching the neurosurgical community's repertoire.

methodsThis was a retrospective cohort study, analyzed patient data from Xuanwu Hospital, between 2017 to 2023. All patients had a history of surgical treatment for CVJ malformations, and experienced failure or loss of reduction. The distance from the odontoid process tip to the Chamberlain's line (DCL), the atlantodental interval (ADI), clivus-canal angle, cervicomedullary angle, width of subarachnoid space, CVJ area, and width of syrinx were used for radiographic assessment. Japanese Orthopaedic Association (JOA) scores and SF-12 scores were used for clinical assessment. Independent sample t-tests were employed. A significance level of p < 0.05 indicates statistically significant differences.

resultsWe analyzed data from 35 patients. For patients who underwent PFDF, the postoperative DCL, ADI, and clivus-canal angle significantly improved. For all patients, the postoperative cervicomedullary angle, width of subarachnoid space, CVJ area, and width of syrinx all demonstrated significant improvement, indicating the relief of neural compression. All patients showed significant improvement in both symptoms and clinical assessments.

conclusionSevere atlantoaxial joint locking or ligament contracting are the fundamental cause of reduction and fixation failure. Anterior odontoidectomy is indicated for patients with robust bony fusion of the atlantoaxial joint in an unreduced position. The PFDF technique is safe and effective for patients with incomplete atlantoaxial bony fusion. Preoperative assessment of surgical feasibility and vertebral artery status ensures surgical safety and efficacy.

Indexed as

Atlanto-Axial JointReoperationSpinal FusionTreatment FailureAdolescentAdultChildFemaleHumansMaleMiddle AgedRetrospective StudiesYoung AdultBasilar invaginationFixationPosterior approachReductionRevision

Identifiers

PMID39187976
PMCPMC11541122

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.