Evidence map›Paper›PMID 39187974›Full record

ArticleCNS neuroscience & therapeutics2024

Resting-state functional connectivity of the occipital cortex in different subtypes of Parkinson's disease.

Yina Lan, Hongjun Yuan, Xiaoxaio Ma, ChunYu Yin, Xinyun Liu, XiYu Zeng, Jinhao Lyu, Yongqin Xiong, Xiaobo Zhang, Haoxuan Lu and 4 more

Abstract read
In one paragraph

Article in CNS neuroscience & therapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Relationship between excessive daytime sleepiness and motor subtype transition in untreated prodromal Parkinson's disease: a cohort study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2026
    Article
  2. Article
  3. A Network Centered on the Visual-Motor Cortex Is Critically Involved in Postural Abnormality in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2026
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yina LanDepartment of Radiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Hongjun YuanDepartment of Radiology, The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
Xiaoxaio MaDepartment of Radiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
ChunYu YinDepartment of Cadres' Outpatient, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Xinyun LiuDepartment of Radiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
XiYu ZengDepartment of Radiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Jinhao LyuDepartment of Radiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Yongqin XiongDepartment of Radiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Xiaobo ZhangDepartment of Radiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Haoxuan LuDepartment of Radiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Yujue ZhongDepartment of Radiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Xuemei LiDepartment of Cadres' Outpatient, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Zhiqiang CuiDepartment of Neurosurgery, The First Medical Center of Chinese PLA General Hospital, Beijing, China.
Xin LouDepartment of Radiology, The First Medical Center of Chinese PLA General Hospital, Beijing, China.ORCID 0000-0003-2980-5171

Funding

National Natural Science Foundation of China 81825012National Natural Science Foundation of China 82151309National Natural Science Foundation of China 82302146Youth Independent Innovation Science Foundation of PLA General Hospital 22QNFC077
6 · The paper itself

Abstract

aimsTo examine whether functional connectivity (FC) of the occipital gyrus differs between patients with Parkinson's disease (PD) motor subtypes and healthy controls (HCs).

methodsWe enrolled 30 PD patients exhibiting tremor dominance (TD), 43 PD patients with postural instability and gait disturbance (PIGD), and 42 HCs. The occipital gyrus was partitioned into six areas of interest, as seed points, via the Anatomical Automatic Labeling template to compare the FC of the three groups and analyze the relationship of FC with clinical scales.

resultsCompared with the PIGD group, the TD group showed increased FC between the left superior occipital gyrus (SOG.L) and right median cingulate and paracingulate gyri (DCG.R)/right paracentral lobule/bilateral inferior parietal, but supramarginal and angular gyri; the left middle occipital gyrus (MOG.L) and left posterior cingulate gyrus (PCG.L); the MOG.R and SOG.L/right calcarine fissure and surrounding cortex/DCG.R/PCG.L/right cuneus; the left inferior occipital gyrus (IOG.L) and right caudate nucleus; and the IOG.R and PCG.L.

conclusionDifferentiated FC between the occipital gyrus and other brain areas within the PD motor subtypes, which may serve as neural markers to distinguish between patients with TD and PIGD PD.

Indexed as

Neural PathwaysOccipital LobeParkinson DiseaseAgedFemaleHumansMaleMiddle AgedRetrospective Studiesfunctional connectivitymotor subtypeParkinson's disease

Identifiers

PMID39187974
PMCPMC11347390

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.