Evidence map›Paper›PMID 39187852›Full record

ArticleBMC musculoskeletal disorders2024

A novel cervical vertebral bone quality score can independently predict cage subsidence after anterior cervical corpectomy and fusion.

Junhu Li, Linnan Wang, Zhipeng Deng, Shuxin Zheng, Lei Wang, Yueming Song

Abstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. The predictive value of MRI-based vertebral bone quality score for adjacent segment degeneration following single-level anterior cervical fusion.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  3. C-VBQ and CT hounsfield units for DXA-defined low bone mass screening and their associations with bone turnover markers.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  4. Local fragility index and Radiomics-lite modeling of CT-Derived Hounsfield units for osteoporosis risk assessment in spine surgery patients.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
  5. Article
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Junhu Li *Department of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital and West China, School of Medicine, Sichuan University, Chengdu, 610041, P.R. China.
Linnan Wang *Department of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital and West China, School of Medicine, Sichuan University, Chengdu, 610041, P.R. China.
Zhipeng DengDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital and West China, School of Medicine, Sichuan University, Chengdu, 610041, P.R. China.
Shuxin ZhengDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital and West China, School of Medicine, Sichuan University, Chengdu, 610041, P.R. China.
Lei WangDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital and West China, School of Medicine, Sichuan University, Chengdu, 610041, P.R. China. wanglei_cd@126.com.
Yueming SongDepartment of Orthopedic Surgery and Orthopedic Research Institute, West China Hospital and West China, School of Medicine, Sichuan University, Chengdu, 610041, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo optimize cervical vertebral bone quality (C-VBQ) score and explore its effectiveness in predicting cage subsidence in Anterior Cervical Corpectomy and Fusion (ACCF) and identify a new method for evaluating subsidence without different equipment and image scale interference.

methodsCollecting demographic, imaging, and surgical related information. Measuring Cage Subsidence with a new method. Multifactorial logistic regression was used to identify risk factors associated with subsidence. Pearson's correlation was used to determine the relationship between C-VBQ and computed tomography (CT) Hounsfield units (HU). The receiver operating characteristic (ROC) curve was used to assess C-VBQ predictive ability. Correlations between demographics and C-VBQ scores were analyzed using linear regression models.

results92 patients were included in this study, 36 (39.1%) showed subsidence with a C-VBQ value of 2.05 ± 0.45, in the no-subsidence group C-VBQ Value was 3.25 ± 0.76. The multifactorial logistic regression showed that C-VBQ is an independent predictor of cage subsidence with a predictive accuracy of 93.4%. Pearson's correlation analysis showed a negative correlation between C-VBQ and HU values. Linear regression analysis showed a positive correlation between C-VBQ and cage subsidence. Univariate analyses showed that only age was associated with C-VBQ.

conclusionsThe C-VBQ values obtained using the new measurements independently predicted postoperative cage subsidence after ACCF and showed a negative correlation with HU values. By adding the measurement of non-operated vertebral heights as a control standard, the results of cage subsidence measured by the ratio method are likely to be more robust, perhaps can exclude unavoidable errors caused by different equipment and proportional.

Indexed as

Cervical VertebraeSpinal FusionAdultAgedBone DensityFemaleHumansMaleMiddle AgedPostoperative ComplicationsPredictive Value of TestsRetrospective StudiesRisk FactorsTomography, X-Ray ComputedAnterior cervical corpectomy and fusionCage subsidenceC-VBQ scoreHounsfield unitMRI

Identifiers

PMID39187852
PMCPMC11345962

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.