Evidence map›Paper›PMID 39187694›Full record

ArticleAbdominal radiology (New York)2025

Salient magnetic resonance imaging findings in the differential diagnosis of benign, borderline and malignant ovarian mucinous tumors.

Safa Ozyilmaz, Fatma Kulali, Cumhur Selcuk Topal, Cem Yalcinkaya

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Article in Abdominal radiology (New York), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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3 citing papers in PubMed.

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5 · Who and what money

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4 authors.

Safa Ozyilmaz *Department of Radiology, University of Health Sciences, Umraniye Training and Research Hospital, Adem Yavuz street. No:1, Umraniye, Istanbul, 34764, Turkey.ORCID 0009-0002-2041-1037
Fatma Kulali *Department of Radiology, University of Health Sciences, Umraniye Training and Research Hospital, Adem Yavuz street. No:1, Umraniye, Istanbul, 34764, Turkey. ftkulali@gmail.com.ORCID 0000-0002-9392-6907
Cumhur Selcuk TopalDepartment of Pathology, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkey.ORCID 0000-0001-6782-2373
Cem YalcinkayaDepartment of Gynecologic Oncology, University of Health Sciences, Umraniye Training and Research Hospital, Istanbul, Turkey.ORCID 0000-0001-7533-0838

Funding

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6 · The paper itself

Abstract

purposeIn mucinous ovarian tumors, preoperative prediction of histological subgroup is important for treatment approach. Therefore, we aimed to determine salient magnetic resonance imaging (MRI) findings and estimate optimal cut off values for quantitative features in differential diagnosis of benign, borderline and malignant mucinous ovarian tumors.

methodsBetween January 2011 and December 2021, preoperative MRI scans of 50 patients with mucinous ovarian tumors (n = 54) were evaluated retrospectively. MRI findings [size, signal intensity, contrast pattern, features of loculation, wall, septa and mural nodule (MN), diffusion restriction] were investigated. There were benign, borderline, and malignant groups based on histopathological results. The relationship between radiological and histopathological results was analyzed by performing Kruskal Wallis test, Pearson's chi-squared test, receiver operating characteristic analysis.

resultsIn our study, there were 54 mucinous ovarian tumors in 50 patients. Of 54, 33 were benign, 13 borderline and eight malignant tumors. In comparison of three groups, tumor size, number of loculation, number and frequency of MN were higher and apparent diffusion coefficient (ADC) value were lower in malignant group (p < 0.05). Septa thickness was lower with optimal cut off value of 2.45 mm in benign group compared to borderline and malignant groups [sensitivity: 79%, specificity: 75%, AUC (Area under the curve): 0.861] (p < 0.05). T2-weighted (T2-w) signal intensity ratio (SIR) of MN was higher in borderline compared to malignant group, with a cut-off value of 3.9 (sensitivity: 85%, specificity: 83%, AUC: 0.943) (p < 0.05). Ascites was also significant in malignant group (p < 0.05).

conclusionT2-w SIR of MN with a cut off value of 3.9 is beneficial for differential diagnosis. By awareness of some salient MRI findings (size, septa thickness, number of loculation, number and T2-w SIR of MN, ADC value and ascites), preoperative prediction of histological subgroup of mucinous tumors for appropriate treatment planning is possible.

Indexed as

Adenocarcinoma, MucinousMagnetic Resonance ImagingOvarian NeoplasmsAdultAgedContrast MediaDiagnosis, DifferentialFemaleHumansMiddle AgedRetrospective StudiesSensitivity and SpecificityContrast MediaBenignBorderlineMagnetic resonance imagingMalignantMucinousOvarian tumor

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PMID39187694

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