Evidence map›Paper›PMID 39187354›Full record

Trial reportIn vivo (Athens, Greece)

Management of the Axilla After Neoadjuvant Chemotherapy: Can Axillary Needle Biopsy Replace Sentinel Node Biopsy?

Emine Yildirim, Pelin Basim, Nese Ucar, Sibel Bektas, Kutay Iscen, Ebru Karci, Asena Ayca Ozdemir

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Emine YildirimDepartment of General Surgery, University of Health Sciences, Gaziosmanpasa Training and Research Hospital, Istanbul, Turkey; opdreyildirim@gmail.com.
Pelin BasimDepartment of General Surgery, Istanbul Medipol University, Faculty of Medicine, Istanbul, Turkey.
Nese UcarDepartment of Radiology, University of Health Sciences, Gaziosmanpasa Training and Research Hospital, Istanbul, Turkey.
Sibel BektasDepartment of Pathology, University of Health Sciences, Gaziosmanpasa Training and Research Hospital, Istanbul, Turkey.
Kutay IscenDepartment of General Surgery, University of Health Sciences, Gaziosmanpasa Training and Research Hospital, Istanbul, Turkey.
Ebru KarciDepartment of Oncology, Istanbul Medipol University, Faculty of Medicine, Istanbul, Turkey.
Asena Ayca OzdemirDepartment of Medical Education, Faculty of Medicine, Mersin University, Mersin, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimThe aim of the study was to investigate whether it is possible to evaluate the axilla after treatment without performing sentinel lymph node biopsy (SLNB) in breast cancer patients with biopsy-proven axillary lymph node metastases who received neoadjuvant chemotherapy (NAC). PATIENTS AND

methodsThis prospective, randomized, clinically designed study included patients with clinical T

resultsThe study included 50 female patients with breast cancer, with a mean age of 48.4±10.72 years. In both groups, metastasis was detected in nine patients, and no metastasis was seen in 14 patients. In intergroup comparisons, all patients with metastasis in the FNAB group also had metastasis according to SLNB, while 21.4% of the cases without metastasis in this group were metastatic according to SLNB. In the CNB group, metastasis was observed in all patients with metastasis according to SLNB, while no metastasis was detected in those who were reported to have no metastasis by SLNB. The accuracy, specificity, and sensitivity values for the prediction of SLNB results were all found to be 100% for CNB, whereas they were 87%, 100%, and 75%, respectively, for FNAB.

conclusionBoth CNB and FNAB could potentially replace SLNB due to their high accuracy rates in evaluating the axilla after NAC. The sensitivity and accuracy of CNB were determined to be higher.

Indexed as

AxillaBreast NeoplasmsLymphatic MetastasisNeoadjuvant TherapySentinel Lymph Node BiopsyAdultBiopsy, Fine-NeedleFemaleHumansLymph NodesMiddle AgedNeoplasm StagingProspective Studiesaxillary lymph node dissectionaxillary managementBreast cancerneoadjuvant chemotherapysentinel lymph node biopsy

Identifiers

PMID39187354
PMCPMC11363797

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.