Evidence map›Paper›PMID 39187345›Full record

ArticleIn vivo (Athens, Greece)

A Rapidly Developing Nodule in a Patient With Hairy Cell Leukemia in Remission: Merkel Cell Carcinoma: A Case Report.

Sotirios Sachanas, Christina Stefanaki, Leonidas Marinos, Xanthi Yiakoumis, Maria Moschogiannis, Efstathios Koulieris, Maria Efstathopoulou, Gerassimos A Pangalis

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sotirios SachanasDepartment of Hematology, Athens Medical Center-Psychikon Branch, Athens, Greece; ssachanas@gmail.com.
Christina StefanakiAthens Medical Center-Psychikon Branch, Athens, Greece.
Leonidas MarinosDepartment of Hematopathology, Evangelismos General Hospital, Athens, Greece.
Xanthi YiakoumisDepartment of Hematology, Athens Medical Center-Psychikon Branch, Athens, Greece.
Maria MoschogiannisDepartment of Hematology, Athens Medical Center-Psychikon Branch, Athens, Greece.
Efstathios KoulierisDepartment of Hematology, Athens Medical Center-Psychikon Branch, Athens, Greece.
Maria EfstathopoulouDepartment of Hematology, Athens Medical Center-Psychikon Branch, Athens, Greece.
Gerassimos A PangalisDepartment of Hematology, Athens Medical Center-Psychikon Branch, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimHairy cell leukemia (HCL) is a well-known lymphoproliferative disease with very effective treatment approaches primarily relying on purine analogues. However, these treatments are associated with profound and prolonged immunosuppression. Merkel cell carcinoma (MCC) is a rare and extremely aggressive skin tumor with an increased incidence in immunocompromised patients. CASE REPORT: We report a case of a patient with HCL who was diagnosed with MCC, while in remission following retreatment with pentostatin, which induced a profound decrease in CD4 (+) T-cells.

conclusionOur case provides further evidence supporting the hypothesis of a significant association between immunosuppression and MCC pathogenesis.

Indexed as

Carcinoma, Merkel CellLeukemia, Hairy CellBiopsyHumansPentostatinRemission InductionSkin NeoplasmsPentostatinHairy cell leukemiaimmunosuppressionMerkel cell carcinomapentostatin

Identifiers

PMID39187345
PMCPMC11363770

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.