Evidence map›Paper›PMID 39187326›Full record

ArticleIn vivo (Athens, Greece)

Toward Inclusive Oncology: Challenges in the Therapy of Pediatric Non-B Non-Hodgkin Lymphomas.

Joanna Stankiewicz, Anna Jabłońska, Paweł Treichel, Jan Styczyński

Abstract read
In one paragraph

Article in In vivo (Athens, Greece). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Joanna StankiewiczDepartment of Pediatric Hematology and Oncology, Collegium Medicum, Nicolaus Copernicus University Torun, Antoni Jurasz University Hospital No. 1, Bydgoszcz, Poland; joanna.konieczek@cm.umk.pl.
Anna JabłońskaStudent Scientific Society, Department of Pediatric Hematology and Oncology, Collegium Medicum, Nicolaus Copernicus University Torun, Antoni Jurasz University Hospital No. 1, Bydgoszcz, Poland.
Paweł TreichelStudent Scientific Society, Department of Pediatric Hematology and Oncology, Collegium Medicum, Nicolaus Copernicus University Torun, Antoni Jurasz University Hospital No. 1, Bydgoszcz, Poland.
Jan StyczyńskiDepartment of Pediatric Hematology and Oncology, Collegium Medicum, Nicolaus Copernicus University Torun, Antoni Jurasz University Hospital No. 1, Bydgoszcz, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

aimNon-B non-Hodgkin lymphomas (NHL) represent over 30 T/NK lymphoma types. The majority of them are T-cell lymphoblastic lymphomas (TLL) and anaplastic large cell lymphomas (ALCL). Other rare non-B NHLs represent a diverse group of neoplasms, usually excluded from clinical trials. This study analyzed outcomes in pediatric patients with non-B NHL in a single oncology center with particular emphasis on patients with rare NHLs. PATIENTS AND

methodsWe retrospectively analyzed data from patients <18 years with newly diagnosed non-B NHL treated at the Department of Pediatric Hematology and Oncology in Bydgoszcz between 2002 and 2022. The probability of 5-year overall survival (pOS) and event-free survival (pEFS) were calculated for the entire cohort and patients with TLL and ALCL. The clinical course for patients with rare non-B NHL was described in detail.

resultsTwenty-six children were eligible for analysis. Fourteen patients were diagnosed with ALCL, nine with TLL, and three with rare NHL types (subcutaneous panniculitis-like T-cell lymphoma, extranodal NK/T-cell lymphoma and hydroa vacciniforme-like lymphoproliferative disease associated lymphoma). For the entire group, the 5-year pOS was 83.7% and the 5-year pEFS was 72.4%. For TLL and ALCL, the outcomes were comparable with those achieved in clinical trials. Patients with rare NHL were treated according to individualized therapy recommendations based on physicians' expertise and available case report descriptions.

conclusionThere is a lack of knowledge on optimal therapeutic strategies for rare NHLs. It is crucial to create trials dedicated to uncommon NHLs and establish therapy guidelines for these patients.

Indexed as

Lymphoma, Non-HodgkinAdolescentChildChild, PreschoolDisease ManagementFemaleHumansMaleMedical OncologyPrognosisRetrospective StudiesTreatment Outcomechildrennon-B NHLNon-Hodgkin lymphomarare malignancies

Identifiers

PMID39187326
PMCPMC11363777

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.