Evidence map›Paper›PMID 39186734›Full record

ArticleMedicine and science in sports and exercise2025

Determining Individualized Foot Progression Angle for Reduction of Knee Medial Compartment Loading during Stepping.

Raziyeh Baghi, Wei Yin, Ahmed Ramadan, Subham Badhyal, Giovanni Oppizzi, Dali Xu, Peter Bowman, Frank Henn, Li-Qun Zhang

Abstract read
In one paragraph

Article in Medicine and science in sports and exercise, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Effects of Subject-Specific Robot-Guided Off-Axis Stepping Training in Individuals With Medial Knee Osteoarthritis.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Raziyeh BaghiUniversity of Maryland Baltimore, Baltimore, MD.
Wei YinUniversity of Maryland Baltimore, Baltimore, MD.
Ahmed Ramadan
Subham Badhyal
Giovanni Oppizzi
Dali XuUniversity of Maryland Baltimore, Baltimore, MD.
Peter BowmanUniversity of Maryland Baltimore, Baltimore, MD.
Frank HennUniversity of Maryland Baltimore, Baltimore, MD.

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI Stephen L. Seliger · 2006 to 2026
$28.9M
ACL HHS 90ARHF0009ACL HHS 90REMM0001NIA NIH HHS P30 AG028747
6 · The paper itself

Abstract

purposeModifying foot progression angle (FPA), the angle between the line from the heel to the second metatarsal head and the line of progression, can reduce peak knee adduction moment (pKAM). However, determining the optimal FPA that minimizes pKAM without inducing unnatural walking patterns can be challenging. This study investigated the FPA-pKAM relationship using a robotic stepping trainer to assess the feasibility of determining the optimal FPA based on this relationship. In addition, it examined knee moments during stepping with three different FPAs, as stepping is a recommended exercise for knee osteoarthritis rehabilitation.

methodsTwenty-six asymptomatic individuals stepped on a robotic stepping trainer, which measured six-axis footplate-reaction forces/torques and three-dimensional ankle kinematics to determine external knee moments. The robot rotated the footplates slowly (~0.5 deg·s -1 ) between 10°-toe-out and 10°-toe-in while participants stepped continuously, unaware of the footplate rotations. The slope of pKAM-FPA relationship during continuous stepping was determined. Peak three-dimensional knee moments were compared between the 10°-toe-in, 0°-FPA, and 10°-toe-out FPAs with repeated-measures ANOVA. Multiple linear regression determined the covariates that predicted pKAM during stepping.

resultsEighteen participants had lower pKAM and KAM impulse with 10°-toe-in than 10°-toe-out ( P < 0.001) and 0°-FPA ( P < 0.001 and P = 0.008, respectively; called toe-in responders). Conversely, eight participants reduced pKAM and KAM impulse with 10°-toe-out compared with 0°-FPA ( P < 0.001, P = 0.017) and 10°-toe-in ( P = 0.026, P = 0.004; called toe-out responders). A linear pKAM-FPA relationship was determined for each individual, and its slope (the pKAM rate with FPA) was positive for toe-in responders ( P < 0.01) and negative for toe-out responders ( P = 0.02). Regression analysis revealed that smaller pKAM with toe-in, in toe-in responders, was explained by increased tibia medial tilt, tibia internal rotation, footplate-reaction lateral force, footplate-reaction anterior force, and decreased footplate-reaction internal rotation torque.

conclusionsIndividuals may exhibit different responses to FPA modification during stepping. The slope and intercept of the linear pKAM-FPA relationship can be determined for individual subjects. This allows for a targeted pKAM reduction through guided FPA positioning and potentially offers subject-specific precision knee osteoarthritis rehabilitation.

Indexed as

FootKnee JointAdultBiomechanical PhenomenaFemaleHumansMaleOsteoarthritis, KneeRoboticsWalkingWeight-BearingYoung Adult

Identifiers

PMID39186734
PMCPMC12411098

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.