SynthesisPloS one2024
The impact of sarcopenia on the incidence of postoperative outcomes following spine surgery: Systematic review and meta-analysis.
Synthesis in PloS one, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Cervical sarcopenia and frailty as complementary predictors of postoperative outcomes after odontoid fracture fixation: a retrospective cohort study in the United States.Asian spine journal · 2026Article
- Associations of paraspinal muscle quantity and quality with patient-reported outcomes in patients aged ≥85 years undergoing lumbar spine surgery: an exploratory retrospective study.Journal of spine surgery (Hong Kong) · 2026Article
- Exploring the role of frailty and sarcopenia in predicting postoperative regret and satisfaction following adult spinal deformity surgery.Spine deformity · 2026Article
- Opportunistic CT-Based Sarcopenia Screening: Masseter Muscle Index as a Prognostic Indicator of Prolonged Hospitalization in Carotid Endarterectomy.Diagnostics (Basel, Switzerland) · 2026Article
- Exploring the role of frailty and sarcopenia in predicting postoperative regret and satisfaction following adult spinal deformity surgery.Spine deformity · 2026Article
- Development of a risk scoring system for surgical site infection after lumbar surgery using Dixon MRI and clinical parameters.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
- Impact of sarcopenia on outcomes following vertebral augmentation for osteoporotic vertebral compression fracture: a systematic review and meta-analysis.Asian spine journal · 2025Article
- Fatty infiltration in the multifidus predicts screw-loosening following short-segment decompression and fusion: proof of why we should protect and rehabilitate the paraspinal muscles.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025Article
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Authors and funding
18 authors.
Funding
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Abstract
purposeSarcopenia is considered to be an important predictor of adverse outcomes following spinal surgery, but the specific relationship between the two is not clear. The purpose of this meta-analysis is to systematically review all relevant studies to evaluate the impact of sarcopenia on spinal surgery outcomes.
methodsWe systematically searched PubMed, Embase and the Cochrane Library for relevant articles published on or before January 9, 2023. The pooled odds ratio (OR) with 95% confidence intervals (CIs) was calculated in a random effects meta-analysis. The main outcome was the risk of adverse outcomes after spinal surgery, including adverse events and mortality. This systematic review and meta-analysis was conducted following the PRISMA guidelines to evaluate the impact of sarcopenia on spinal surgery outcomes. In addition, we also conducted a subgroup analysis and leave-one-out sensitivity analyses to explore the main sources of heterogeneity and the stability of the results.
resultsTwenty-four cohort studies, with a total of 243,453 participants, met the inclusion criteria. The meta-analysis showed that sarcopenia was significantly associated with adverse events (OR 1.63, 95% CI 1.17-2.27, P < 0.001) but was no significantly associated with mortality (OR 1.17, 95% CI 0.93-1.46, P = 0.180), infection (OR 2.24, 95% CI 0.95-5.26, P < 0.001), 30-day reoperation (OR 1.47, 95% CI 0.92-2.36, P = 0.413), deep vein thrombosis (OR 1.78, 95% CI 0.69-4.61, P = 0.234), postoperative home discharge (OR 0.60, 95% CI 0.26-1.37, P = 0.002) and blood transfusion (OR 3.28, 95% CI 0.74-14.64, P = 0.015).
conclusionThe current meta-analysis showed that patients with sarcopenia have an increased risk of adverse events and mortality after spinal surgery. However, these results must be carefully interpreted because the number of studies included is small and the studies are significantly different. These findings may help to increase the clinicians' awareness of the risks concerning patients with sarcopenia to improve their prognosis.
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