Evidence map›Paper›PMID 39186649›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Conserved moonlighting protein pyruvate dehydrogenase induces robust protection against

Xiaolei Wang, Ying Dou, Jingchu Hu, Celia Hoi-Ching Chan, Renhao Li, Li Rong, Huarui Gong, Jian Deng, Terrence Tsz-Tai Yuen, Xuansheng Lin and 7 more

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Conserved CD4Nature microbiology · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Conserved moonlighting protein pyruvate dehydrogenase induces robust protection againstProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Xiaolei Wang *School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.ORCID 0000-0003-3280-7282
Ying Dou *School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Jingchu Hu *School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.ORCID 0000-0001-6144-7226
Celia Hoi-Ching Chan *School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Renhao LiSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Li RongSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Huarui GongChinese Academy of Sciences Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, Shenzhen, People's Republic of China.
Jian DengKey Laboratory for Experimental Teratology of Ministry of Education and Advanced Medical Research Institute, Cheeloo College of Medicine, Shandong University, Jinan, People's Republic of China.
Terrence Tsz-Tai YuenDepartment of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Xuansheng LinSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Yige HeSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Canhui SuSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Bao-Zhong ZhangSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Jasper Fuk-Woo ChanDepartment of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Kwok-Yung YuenDepartment of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Hin ChuDepartment of Microbiology, School of Clinical Medicine, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.
Jian-Dong HuangSchool of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.ORCID 0000-0001-7531-2816

Funding

Health and Medical Research Fund (HMRF) CID-HKU1Health and Medical Research Fund (HMRF) COVID1903010Health and Medical Research Fund (HMRF) T-11-709/21-NMOST | National Key Research and Development Program of China (NKPs) 2018YFA0902701MOST | National Key Research and Development Program of China (NKPs) 2021YFA0910700MOST | National Key Research and Development Program of China (NKPs) 2021YFC0866100Research Grants Council, University Grants Committee () 17124921
6 · The paper itself

Abstract

Developing an effective

Indexed as

Staphylococcal InfectionsStaphylococcal VaccinesStaphylococcus aureusAnimalsAntibodies, BacterialBacterial ProteinsDisease Models, AnimalFemaleHumansMethicillin-Resistant Staphylococcus aureusMiceMice, Inbred C57BLPyruvate Dehydrogenase ComplexPyruvate Dehydrogenase (Lipoamide)Antibodies, BacterialBacterial ProteinsPyruvate Dehydrogenase ComplexPyruvate Dehydrogenase (Lipoamide)Staphylococcal Vaccinesmoonlighting proteinS. aureus vaccineγδ T cell

Identifiers

PMID39186649
PMCPMC11388329

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.