Evidence map›Paper›PMID 39186476›Full record

ArticleChemistry (Weinheim an der Bergstrasse, Germany)2024

Determining Ion-Pair Binding Affinities of Heteroditopic Receptor Systems.

Andrew Docker, Hui Min Tay

Abstract read
In one paragraph

Article in Chemistry (Weinheim an der Bergstrasse, Germany), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Determining Ion-Pair Binding Affinities of Heteroditopic Receptor Systems.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Andrew DockerYusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, UK.ORCID https://orcid.org/0009-0002-7101-0284
Hui Min TayDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, Mansfield Road, Oxford, OX1 3TA, UK.

Funding

Gonville and Caius College, University of Cambridge
6 · The paper itself

Abstract

Determining ion-pair affinities in heteroditopic receptor systems presents a persistent and significant challenge. The plethora of technical and experimental problems implicated in measuring ion-pair affinities have encouraged the use of several expedient experimental practices as a means of characterising ion-pair recognition behaviour. Exploiting a model heteroditopic receptor system, we interrogate the reliability of these methods and demonstrate that these commonly used techniques can be highly questionable and without extreme care can lead to incorrect conclusions.

Indexed as

Chalcogen BondingHeteroditopic ReceptorsIon-Pair Recognition

Identifiers

PMID39186476
PMCPMC11618037

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.