Evidence map›Paper›PMID 39186220›Full record

ArticleJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs2025

A case of successful surgical treatment of left ventricular thrombus associated with acute myocardial infarction by Impella combined with extracorporeal membrane oxygenation approach.

Rieko Kutsuzawa, Naoki Tadokoro, Satoshi Kainuma, Naonori Kawamoto, Kouta Suzuki, Ayumi Ikuta, Kohei Tonai, Masaya Hirayama, Yoshiyuki Tomishima, Yasuhide Asaumi and 1 more

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In one paragraph

Article in Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. The first case of central Y-Y extra-corporeal membrane oxygenation system in a pediatric patient.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rieko KutsuzawaDepartment of Cardiac Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Naoki TadokoroDepartment of Cardiac Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan. naoki.tadokoro87@gmail.com.ORCID http://orcid.org/0000-0002-4658-852X
Satoshi KainumaDepartment of Cardiac Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Naonori KawamotoDepartment of Cardiac Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Kouta SuzukiDepartment of Cardiac Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Ayumi IkutaDepartment of Cardiac Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Kohei TonaiDepartment of Cardiac Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Masaya HirayamaDepartment of Cardiac Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Yoshiyuki TomishimaDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Yasuhide AsaumiDepartment of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan.
Satsuki FukushimaDepartment of Cardiac Surgery, National Cerebral and Cardiovascular Center, Suita, Osaka, Japan. s.fukushima@ncvc.go.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The mortality rate in patients with heart failure complicated by cardiogenic shock following acute myocardial infarction (AMI) remains high, prompting research on mechanical circulatory support. Improved mortality rates have been reported with the early introduction of EcMELLA (Impella combined with extracorporeal membrane oxygenation, ECMO). However, clear indications for this treatment have not been established, given the associated risks and limitations related to access routes. Left ventricular thrombosis is traditionally considered a contraindication for Impella use. A 74-year-old man without specific medical history or coronary risk factors was diagnosed with Forrester IV heart failure due to cardiogenic shock complicated by AMI and left ventricular thrombosis. The patient underwent emergency coronary artery bypass surgery, intracardiac thrombus removal, and Dor surgery. Following cardiopulmonary bypass, ongoing heart failure was observed, necessitating the implementation of EcMELLA for circulatory support. Preoperative computed tomography showed that the bilateral subclavian arteries were too narrow (< 7 mm) and anatomically unsuitable for traditional access methods. Thus, we introduced a single-access EcMELLA 5.5, through which the Impella was introduced and veno-arterial-ECMO blood was delivered from a single artificial vessel anastomosed to the brachiocephalic artery. The patient was weaned off veno-arterial-ECMO and extubated on postoperative day 3. By postoperative day 14, improved cardiac function allowed for Impella removal. The patient was discharged on postoperative day 31 with improved ambulation; thereafter, the patient returned to work. Thus, the single-access EcMELLA5.5 treatment strategy combined with Dor procedure was effective in left ventricular thrombosis in patients with heart failure with cardiogenic shock complicated by AMI.

Indexed as

Extracorporeal Membrane OxygenationHeart-Assist DevicesHeart FailureHeart VentriclesMyocardial InfarctionThrombosisAgedHumansMaleShock, CardiogenicAcute myocardial infarctionDor procedureEcMELLAHeart failureLeft ventricular thrombus

Identifiers

PMID39186220

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.