Evidence map›Paper›PMID 39186148›Full record

ArticleArchives of toxicology2024

Effects of metal oxide nanoparticles on healthy and psoriasis-like human epidermal keratinocytes in vitro.

Li Yi Tan, Magdiel Inggrid Setyawati, Kee Woei Ng

Abstract read
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In one paragraph

Article in Archives of toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Li Yi TanSchool of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Ave, Singapore, 639798, Singapore.ORCID 0000-0002-5224-2453
Magdiel Inggrid SetyawatiSchool of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Ave, Singapore, 639798, Singapore.ORCID 0000-0002-3221-077X
Kee Woei NgSchool of Materials Science and Engineering, Nanyang Technological University, 50 Nanyang Ave, Singapore, 639798, Singapore. kwng@ntu.edu.sg.ORCID 0000-0002-7276-3563

Funding

Ministry of Education - Singapore AcRF Tier 1: RG7/22
6 · The paper itself

Abstract

The use of metal oxide nanoparticles (NPs) in skincare products has significantly increased human skin exposure, raising safety concerns. Whilst NP's ability to penetrate healthy skin is minimal, studies have demonstrated that metal oxide NPs can induce toxicity in keratinocytes through direct contact. Moreover, NP's effect on common skin disorders like psoriasis, where barrier impairments and underlying inflammation could potentially increase NP penetration and worsen nanotoxicity is largely unstudied. In this paper, we investigated whether psoriasis-like human keratinocytes (Pso HKs) would exhibit heightened toxic responses to titanium dioxide (TiO

Indexed as

Cell SurvivalKeratinocytesMetal NanoparticlesOxidative StressPsoriasisSilicon DioxideTitaniumZinc OxideCells, CulturedCytokinesEpidermisHumansInflammasomesCytokinesInflammasomesSilicon DioxideTitaniumtitanium dioxideZinc OxideNanoparticlesSilicaSkin nanotoxicologyTitanium dioxideTrappin-2Zinc oxide

Identifiers

PMID39186148

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.