Evidence map›Paper›PMID 39186141›Full record

ArticleEsophagus : official journal of the Japan Esophageal Society2024

Association of gastric myotomy length in peroral endoscopic myotomy (POEM) with gastro-esophageal junction distensibility measured by Endoluminal Functional Lumen Imaging Probe (EndoFLIP).

Yusuke Fujiyoshi, Mary Raina Angeli Fujiyoshi, Kareem Khalaf, Gary R May, Christopher W Teshima

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Article in Esophagus : official journal of the Japan Esophageal Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

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3citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Yusuke FujiyoshiDepartment of Medicine, Division of Gastroenterology, University of Ottawa, The Ottawa Hospital Research Institute, Ottawa, ON, Canada. yusukefujiyoshi@yahoo.co.jp.ORCID 0000-0002-5893-6552
Mary Raina Angeli FujiyoshiDepartment of Medicine, Division of Gastroenterology, University of Ottawa, The Ottawa Hospital Research Institute, Ottawa, ON, Canada.
Kareem KhalafDivision of Gastroenterology, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Gary R MayDivision of Gastroenterology, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.
Christopher W TeshimaDivision of Gastroenterology, St. Michael's Hospital, University of Toronto, Toronto, ON, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEndoluminal Functional Lumen Imaging Probe (EndoFLIP) is a device that measures gastro-esophageal junction (GEJ) distensibility. However, it is not demonstrated that GEJ distensibility increases proportionally with varying gastric myotomy length in peroral endoscopic myotomy (POEM). This study aimed to investigate the association between gastric myotomy length in POEM and intraoperative EndoFLIP findings.

methodsThis single-center, retrospective cohort study included patients who underwent POEM with intraoperative EndoFLIP from December 2019 to January 2023. Using EndoFLIP, minimal balloon diameter and its distensibility index (DI) were measured pre- and post-myotomy. Primary and secondary outcomes were the post-myotomy EndoFLIP findings at 30 ml and 40 ml volume fills.

resultsThe study included 44 patients (mean age 53.1 years, 50% female). Chicago classification included achalasia type I (39%), II (41%), III (9%), hypercontractile esophagus (2%), and EGJOO (9%). The mean esophageal myotomy length was 7.5 ± 2.2 cm and gastric myotomy was 2.1 ± 0.6 cm. Simple linear regression analyses indicated that for each 1 cm increase in gastric myotomy length, the DI at 30 ml volume fill was estimated to increase by 2.0 mm

conclusionsThis study demonstrates a significant linear relationship between gastric myotomy length and GEJ distensibility measured by EndoFLIP during POEM. These findings may be useful in clinical practice by enabling EndoFLIP to help calibrate a desired gastric myotomy length to achieve optimal DI and minimal diameter.

Indexed as

Esophageal AchalasiaEsophagogastric JunctionMyotomyAdultAgedFemaleHumansMaleManometryMiddle AgedRetrospective StudiesTreatment OutcomeAchalasiaEndoFLIPFunctional lumen imaging probePeroral endoscopic myotomyPOEM

Identifiers

PMID39186141

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.