ArticleBioinformatics (Oxford, England)2024
grenedalf: population genetic statistics for the next generation of pool sequencing.
Article in Bioinformatics (Oxford, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed.
- Genome-Wide SNP Discovery and Population Genomic Characterisation in Indian Major Carp Labeo catla (Hamilton, 1822) Through Low-Depth Whole-Genome Resequencing.Animal genetics · 2026Article
- Virulent Parasites Emerge in Hosts With Rising Temperatures.Global change biology · 2026Article
- Genomic Patterns of Parallel Divergence Across Demographically Heterogeneous Stickleback Populations in Eastern Canada.Genome biology and evolution · 2026Article
- Allele frequency and gene expression differences under key winter stresses in temporal populations of two timothy cultivars.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2026Article
- The illusion of polygenicity in pool-seq genetic mapping studies: insufficient power can mask simple genetic architectures.Genetics · 2026Article
- Storm-induced mass mortality results in both immediate and long-term consequences for a migratory songbird.Nature ecology & evolution · 2026Article
- Graded BMP signals modulate yellow and red color in fishes, impacting adult pigment patterns and conspecific shoaling behavior.Current biology : CB · 2026Article
- Genomic responses to increased temperature and pollinator selection in Brassica rapa L.The New phytologist · 2026Article
- Rapid adaptation and extinction in synchronized outdoor evolution experiments ofScience (New York, N.Y.) · 2026Article
- Transcriptomic signatures of high‑intensity pyrethroid resistance in Anopheles gambiae from a Cameroonian agricultural hotspot.BMC genomics · 2026Article
- Population differences in reproductive resource allocation and heterosis in the invasive vector Aedes albopictus.Parasites & vectors · 2026Article
- Contemporary Evolution of an At-Risk Stickleback Population During a Severe Drought.Evolutionary applications · 2026Article
- Genetic characterization of a global collection of common buckwheat to harness genetic resources for agricultural diversity.Frontiers in plant science · 2026Article
- Genome architecture evolution in an invasive copepod species complex.Nature communications · 2025Article
- Local adaptation of both plant and pathogen: an arms-race compromise in switchgrass rust.The New phytologist · 2025Article
- Analyses of emerging macrocyclic lactone resistance: Speed and signature of ivermectin and moxidectin selection and evidence of a shared genetic locus.PLoS pathogens · 2025Article
- Chromosome-scale genome assembly of the bed bug Cimex lectularius sheds light on a key insecticide resistance locus.G3 (Bethesda, Md.) · 2025Article
- Aphid herbivory on macrophytes drives adaptive evolution in an aquatic community via indirect effects.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Global diversity of soil-transmitted helminths reveals population-biased genetic variation that impacts diagnostic targets.Nature communications · 2025Article
- Pooled, Long-read Sequencing for Structural Variant Characterization in Schistosome Populations.Genome biology and evolution · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
summaryPool sequencing is an efficient method for capturing genome-wide allele frequencies from multiple individuals, with broad applications such as studying adaptation in Evolve-and-Resequence experiments, monitoring of genetic diversity in wild populations, and genotype-to-phenotype mapping. Here, we present grenedalf, a command line tool written in C++ that implements common population genetic statistics such as θ, Tajima's D, and FST for Pool sequencing. It is orders of magnitude faster than current tools, and is focused on providing usability and scalability, while also offering a plethora of input file formats and convenience options. AVAILABILITY AND IMPLEMENTATION: grenedalf is published under the GPL-3, and freely available at github.com/lczech/grenedalf.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.