Observational studyJournal of cachexia, sarcopenia and muscle2024
Body composition parameters in initial CT imaging of mechanically ventilated trauma patients: Single-centre observational study.
Observational study in Journal of cachexia, sarcopenia and muscle, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Computed tomography derived analytic morphomics as predictors of clinical outcomes in trauma: a systematic narrative review.Emergency radiology · 2026Pooled it
- Exploring the association between computed tomography (CT)-derived skeletal muscle mass and short- and long-term mortality in critically ill patients: a systematic review and meta-analysis.Critical care (London, England) · 2025Pooled it
- CT-derived adrenal-to-spleen ratio as a predictor of massive transfusion and mortality in emergency transcatheter arterial embolization of active bleeding.Emergency radiology · 2026Article
- Multimodal Evaluation of Body Composition and Muscle Strength in Women Before and After Bariatric Surgery: A Clinical Observational Study.Medicina (Kaunas, Lithuania) · 2026Observational
- Large language models in emergency and critical care medicine: a comprehensive review of applications, challenges, and future directions.Burns & trauma · 2026Review
- Factors of pre-existing low muscle mass and its relationship with mortality in critically ill patients: a sex-specific analysis.Frontiers in medicine · 2026Article
- Prognostic significance of baseline skeletal muscle index and its dynamics in patients with metastatic breast cancer undergoing eribulin treatment.Breast cancer research and treatment · 2025Article
- The utility of computed tomography-derived inferior vena cava parameters in predicting outcomes in patients with active bleeding undergoing transarterial embolization.International journal of emergency medicine · 2025Article
- The effect of pre-existing sarcopenia on outcomes of critically ill patients treated for COVID-19.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025Article
- Body composition parameters in initial CT imaging of mechanically ventilated trauma patients: Single-centre observational study.Journal of cachexia, sarcopenia and muscle · 2024Observational
Corrections and comments
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBody composition parameters provide relevant prognostic significance in critical care cohorts and cancer populations. Published results regarding polytrauma patients are inconclusive to date. The goal of this study was to analyse the role of body composition parameters in severely injured trauma patients.
methodsAll consecutive patients requiring emergency tracheal intubation and mechanical ventilation before initial computed tomography (CT) at a level-1 trauma centre over a 12-year period (2008-2019) were reanalysed. The analysis included CT-derived body composition parameters based upon whole-body trauma CT as prognostic variables for 30-day mortality, intensive care unit length of stay (ICU LOS) and mechanical ventilation duration.
resultsFour hundred seventy-two patients (75% male) with a median age of 49 years, median injury severity score of 26 and 30-day mortality rate of 22% (104 patients) met the inclusion criteria and were analysed. Regarding body composition parameters, 231 patients (49%) had visceral obesity, 75 patients had sarcopenia (16%) and 35 patients had sarcopenic obesity (7.4%). After adjustment for statistically significant univariable predictors age, body mass index, sarcopenic obesity, visceral obesity, American Society of Anesthesiologists classification ≥3, injury severity score and Glasgow Coma Scale ≤ 8 points, the Cox proportional hazard model identified sarcopenia as significant prognostic factor of 30-day mortality (hazard ratio 2.84; 95% confidence interval 1.38-5.85; P = 0.004), which was confirmed in Kaplan-Meier survival analysis (log-rank P = 0.006). In a subanalysis of 363 survivors, linear multivariable regression analysis revealed no significant associations of body composition parameters with ICU LOS and duration of mechanical ventilation.
conclusionsIn a multivariable analysis of mechanically ventilated trauma patients, CT-defined sarcopenia was significantly associated with 30-day mortality whereas no associations of body composition parameters with ICU LOS and duration of mechanical ventilation were observed.
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