Evidence map›Paper›PMID 39185546›Full record

Observational studyJournal of rehabilitation medicine2024

Classification of upper limb spasticity patterns in patients with multiple sclerosis: a pilot observational study.

Mirko Filippetti, Linde Lugoboni, Rita Di Censo, Luca Degli Esposti, Salvatore Facciorusso, Valentina Varalta, Andrea Santamato, Massimiliano Calabrese, Nicola Smania, Alessandro Picelli

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Journal of rehabilitation medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Mirko FilippettiNeuromotor and Cognitive Rehabilitation Research Center, Section of Physical and Rehabilitation Medicine, Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy; Canadian Advances in Neuro-Orthopedics for Spasticity Consortium (CANOSC), Kingston, ON, Canada.
Linde LugoboniNeuromotor and Cognitive Rehabilitation Research Center, Section of Physical and Rehabilitation Medicine, Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy.
Rita Di CensoNeuromotor and Cognitive Rehabilitation Research Center, Section of Physical and Rehabilitation Medicine, Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy; Neurorehabilitation Unit, Department of Neurosciences, University Hospital of Verona, Italy.
Luca Degli EspostiNeuromotor and Cognitive Rehabilitation Research Center, Section of Physical and Rehabilitation Medicine, Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy.
Salvatore FacciorussoSpasticity and Movement Disorders "ReSTaRt" Unit, Physical Medicine and Rehabilitation Section, Riuniti Hospital, University of Foggia, Foggia, Italy.
Valentina VaraltaNeuromotor and Cognitive Rehabilitation Research Center, Section of Physical and Rehabilitation Medicine, Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy; Neurorehabilitation Unit, Department of Neurosciences, University Hospital of Verona, Italy.
Andrea SantamatoSpasticity and Movement Disorders "ReSTaRt" Unit, Physical Medicine and Rehabilitation Section, Riuniti Hospital, University of Foggia, Foggia, Italy.
Massimiliano CalabreseNeurology Section, Department of Neurosciences, Biomedicine and Movement Sciences, University of Verona, Verona, Italy.
Nicola SmaniaNeuromotor and Cognitive Rehabilitation Research Center, Section of Physical and Rehabilitation Medicine, Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy; Neurorehabilitation Unit, Department of Neurosciences, University Hospital of Verona, Italy.
Alessandro PicelliNeuromotor and Cognitive Rehabilitation Research Center, Section of Physical and Rehabilitation Medicine, Department of Neuroscience, Biomedicine, and Movement Sciences, University of Verona, Verona, Italy; Canadian Advances in Neuro-Orthopedics for Spasticity Consortium (CANOSC), Kingston, ON, Canada; Neurorehabilitation Unit, Department of Neurosciences, University Hospital of Verona, Italy. alessandro.picelli@univr.it.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to provide a classification of the upper limb patterns in patients with upper limb spasticity due to multiple sclerosis.

designPilot observational study. PATIENTS: Twenty-five adult patients with multiple sclerosis suffering from upper limb spasticity who underwent one segmental (i.e., proximal and distal upper limb) botulinum toxin treatment cycle were recruited.

methodsPatients remained in a sitting position during the evaluation. Upper limb spasticity postures (i.e., postural attitude of a single joint/anatomical region) were evaluated and recorded for the shoulder (adducted/internally rotated), elbow (flexed/extended), forearm (pronated/supinated/neutral), wrist (flexed/extended/neutral) and hand (fingers flexed/thumb in palm).

resultsOn the basis of the clinical observations, 6 patterns (i.e., sets of limb postures) of upper limb spasticity have been described according to the postures of the shoulder, elbow, forearm, and wrist.

conclusionThe patterns of upper limb spasticity in patients with multiple sclerosis described by this pilot study do not completely overlap with those observed in patients with post-stroke spasticity. This further supports the need to consider the features of spasticity related to its aetiology in order to manage patients appropriately.

Indexed as

Multiple SclerosisMuscle SpasticityUpper ExtremityAdultAgedFemaleHumansMaleMiddle AgedPilot ProjectsPosture

Identifiers

PMID39185546
PMCPMC11367677

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.