Evidence map›Paper›PMID 39185528›Full record

ArticlemedRxiv : the preprint server for health sciences2024

Nitrous Oxide Alters Functional Connectivity in Medial Limbic Structures in Treatment-Resistant Major Depression.

Charles R Conway, Ben Julian A Palanca, Thomas Zeffiro, Britt M Gott, Frank Brown, Victoria de Leon, Linda Barnes, Thomas Nguyen, Willa Xiong, Christina N Lessov-Schlaggar and 4 more

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Charles R ConwayDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.ORCID 0000-0001-6849-9416
Ben Julian A PalancaDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.
Thomas ZeffiroDepartment of Diagnostic Radiology and Nuclear Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Britt M GottDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.
Frank BrownDepartment of Anesthesia and Critical Care, University of Chicago, Chicago, IL 60637.
Victoria de LeonDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.
Linda BarnesDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.
Thomas NguyenDepartment of Anesthesiology, Washington University School of Medicine, St. Louis, MO 63110.
Willa XiongDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.
Christina N Lessov-SchlaggarDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.
Gemma EspejoDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.
Steven MennerickDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.
Charles F ZorumskiDepartment of Psychiatry, Washington University School of Medicine, St. Louis, MO 63110.
Peter NageleDepartment of Anesthesia and Critical Care, University of Chicago, Chicago, IL 60637.

Funding

Neuroactive steroids as novel psychiatric treatments: mechanistic studiesP50MH122379 · NIMH · WASHINGTON UNIVERSITY · PI MENNERICK, STEVEN J, ZORUMSKI, CHARLES F · 2021 to 2025
$12.2M
PHARMacist and Community Health Support to Optimize Medications After Trauma Surgery (PHARM-C)P50MH122351 · NIMH · WASHINGTON UNIVERSITY · PI Joanna Abraham · 2021 to 2026
$10.8M
Slow Wave Induction by Propofol to Eliminate Depression (SWIPED) TrialU01MH128483 · NIMH · WASHINGTON UNIVERSITY · PI LENZE, ERIC J, PALANCA, BEN JULIAN · 2022 to 2025
$2.8M
GABAA RECEPTOR POPULATIONS IN HIPPOCAMPUS AND THALAMUSR01MH123748 · NIMH · WASHINGTON UNIVERSITY · PI MENNERICK, STEVEN J · 2021 to 2025
$2.4M
NMDA RECEPTOR ANTAGONIST NITROUS OXIDE TARGETS AFFECTIVE BRAIN CIRCUITSR21MH108901 · NIMH · WASHINGTON UNIVERSITY · PI CONWAY, CHARLES RICHARD, NAGELE, PETER · 2016 to 2017
$419k
NIMH NIH HHS P50 MH122351NIMH NIH HHS P50 MH122379NIMH NIH HHS R01 MH123748NIMH NIH HHS R21 MH108901NIMH NIH HHS U01 MH128483
6 · The paper itself

Abstract

While nitrous oxide (N

Identifiers

PMID39185528
PMCPMC11343248

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.