ArticlebioRxiv : the preprint server for biology2024
DNA-PKcs Inhibition Improves Sequential Gene Insertion of the Full-Length
Jacob T Stack, Rachael E Rayner, Reza Nouri, Carlos J Suarez, Sun Hee Kim, Karen L Kanke, Tatyana A Vetter, Estelle Cormet-Boyaka, Sriram Vaidyanathan
Abstract readPreprint
In one paragraphArticle in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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0citing papers in PubMed
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What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registryThe trial behind it
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3 · Its place in the literatureWho cites it
0 citing papers in PubMed.
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4 · The recordCorrections and comments
5 · Who and what moneyAuthors and funding
9 authors.
Jacob T StackCenter for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43215.
Rachael E RaynerDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
Reza NouriCenter for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43215.
Carlos J SuarezDepartment of Pathology, Stanford University, Palo Alto, CA 94305.
Sun Hee KimDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
Karen L KankeCenter for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43215.
Tatyana A VetterCenter for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43215.ORCID 0000-0002-9904-9140 Estelle Cormet-BoyakaDepartment of Veterinary Biosciences, The Ohio State University, Columbus, OH 43210.
Sriram VaidyanathanCenter for Gene Therapy, The Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH 43215.ORCID 0000-0001-9167-3056 Funding
The OSU Center for Clinical and Translational Science: Advancing Today's Discoveries to Improve HealthUL1TR002733 · NCATS · OHIO STATE UNIVERSITY · PI RINGEL, MATTHEW D · 2018 to 2022
$28.9MA universal genome editing strategy to develop an airway stem cell therapy for cystic fibrosisR00HL151900 · NHLBI · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI VAIDYANATHAN, SRIRAM · 2022 to 2024
$747kNCATS NIH HHS UL1 TR002733NHLBI NIH HHS R00 HL151900
6 · The paper itselfAbstract
Cystic fibrosis (CF) is caused by mutations in the cystic fibrosis transmembrane conductance regulator (
Indexed as
airway stem cell therapyCFTR genome editingCFTR super-exonCystic fibrosisDNA-PKcs inhibitionsequential gene insertionuniversal CFTR correction
Identifiers
PMID39185207
PMCPMC11343149
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