Evidence map›Paper›PMID 39185206›Full record

ArticlebioRxiv : the preprint server for biology2024

Novel tau filament folds in individuals with

Manuel Schweighauser, Yang Shi, Alexey G Murzin, Holly J Garringer, Ruben Vidal, Jill R Murrell, M Elena Erro, Harro Seelaar, Isidro Ferrer, John C van Swieten and 3 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Manuel SchweighauserMRC Laboratory of Molecular Biology, Cambridge, UK.
Yang ShiMRC Laboratory of Molecular Biology, Cambridge, UK.
Alexey G MurzinMRC Laboratory of Molecular Biology, Cambridge, UK.
Holly J GarringerDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, USA.
Ruben VidalDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, USA.
Jill R MurrellDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, USA.
M Elena ErroDepartment of Neurology, Hospital Universitario de Navarra, Brain Bank NavarraBiomed, Pamplona, Spain.
Harro SeelaarDepartment of Neurology, Erasmus University, Rotterdam, The Netherlands.
Isidro FerrerDepartment of Pathology and Experimental Therapeutics, University of Barcelona, Spain.
John C van SwietenDepartment of Neurology, Erasmus University, Rotterdam, The Netherlands.
Bernardino GhettiDepartment of Pathology and Laboratory Medicine, Indiana University School of Medicine, Indianapolis, USA.
Sjors H W ScheresMRC Laboratory of Molecular Biology, Cambridge, UK.ORCID 0000-0002-0462-6540
Michel GoedertMRC Laboratory of Molecular Biology, Cambridge, UK.

Funding

Research Education ComponentP30AG010133 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI SAYKIN, ANDREW J · 1991 to 2020
$37.3M
Identification of novel four repeat tauopathies through analysis of network vulnerability, tau structure and propagation.R01AG080001 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI BERNARDINO Francesco GHETTI, RUBEN VIDAL · 2023 to 2026
$2.7M
Structural analysis of tau associated with parenchymal and vascular prion protein amyloidosisRF1AG071177 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI GHETTI, BERNARDINO FRANCESCO, JIANG, WEN · 2021 to 2021
$2.3M
Structural analysis of tau associated with parenchymal and vascular prion protein amyloidosisR01AG071177 · NIA · INDIANA UNIVERSITY INDIANAPOLIS · PI GHETTI, BERNARDINO FRANCESCO, JIANG, WEN · 2024 to 2025
$1.5M
NIA NIH HHS P30 AG010133NIA NIH HHS R01 AG071177NIA NIH HHS R01 AG080001NIA NIH HHS RF1 AG071177
6 · The paper itself

Abstract

Mutations in

Identifiers

PMID39185206
PMCPMC11343192

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.