Evidence map›Paper›PMID 39185183›Full record

ArticlebioRxiv : the preprint server for biology2024

Protein Arginine Methylation of the Translation Initiation Factor eIF1A Increases Usage of a Near-cognate Start Codon.

Rebecca Wegman, Michael Langberg, Richoo B Davis, Xiaozhuo Liu, Minkui Luo, Michael C Yu, Sarah E Walker

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Rebecca WegmanDepartment of Biological Sciences, State University of New York at Buffalo, Buffalo, New York, United States of America.
Michael LangbergChemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.
Richoo B DavisDepartment of Biological Sciences, State University of New York at Buffalo, Buffalo, New York, United States of America.ORCID 0000-0003-3428-3646
Xiaozhuo LiuDepartment of Pharmacology and Therapeutics, Roswell Park Comprehensive Cancer Center, Buffalo, NY.ORCID 0000-0003-2237-1016
Minkui LuoChemical Biology Program, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America.ORCID 0000-0001-7409-7034
Michael C YuDepartment of Biological Sciences, State University of New York at Buffalo, Buffalo, New York, United States of America.ORCID 0000-0002-3611-9295
Sarah E WalkerDepartment of Biological Sciences, State University of New York at Buffalo, Buffalo, New York, United States of America.ORCID 0000-0002-9983-2485

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
Interrogating Protein Methyltransferases with Integrated ApproachesR35GM131858 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI Minkui Luo · 2019 to 2026
$6.3M
Molecular mechanisms of eukaryotic translational controlR01GM139977 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Sarah Elizabeth Walker · 2022 to 2026
$1.8M
Translational control by the eIF4 factorsR00GM119173 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WALKER, SARAH ELIZABETH · 2015 to 2017
$746k
NCI NIH HHS P30 CA008748NIGMS NIH HHS R00 GM119173NIGMS NIH HHS R01 GM139977NIGMS NIH HHS R35 GM131858
6 · The paper itself

Abstract

Protein arginine methylation has emerged as a key post-translational modification responsible for many facets of eukaryotic gene expression. To better understand the extent of this modification in cellular pathways, we carried out bioorthogonal methylation profiling in

Identifiers

PMID39185183
PMCPMC11343201

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.