ArticleNeurology. Clinical practice2024
The Recovery of Consciousness via Evidence-Based Medicine and Research (RECOVER) Program: A Paradigm for Advancing Neuroprognostication.
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Article in Neurology. Clinical practice, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11citing papers in PubMed
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What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Effects of Mechanism of Injury and Time from Injury on Functional Outcomes in Traumatic Brain Injury Patients During Long-Term Acute Care Hospital Rehabilitation.Medicina (Kaunas, Lithuania) · 2026Observational
- Neurological Outcome Beyond the ICU in Patients with Severe Acute Brain Injury: A Knowledge gap for ICU Teams.Journal of intensive care medicine · 2026Observational
- Computed tomography assessment after out-of-hospital cardiac arrest resuscitation.Resuscitation plus · 2026Article
- Article
- Advancing palliative care in cardiac arrest and cardiogenic shock: identifying evidence gaps and future research priorities.Frontiers in cardiovascular medicine · 2026Review
- NeuroRecovery Clinics: A Survey to Understand the Current Landscape and Opinions of Post-NeuroICU Clinics.Critical care explorations · 2025Article
- The miracle dilemma: demystifying a common challenge in neuroprognostication.Brain : a journal of neurology · 2025Article
- Delayed Withdrawal of Life-Sustaining Treatment in Disorders of Consciousness: Practical and Theoretical Considerations.Neurocritical care · 2025Review
- Implementation of a specialized neuroprognostication consultation program and associated provider attitudes: A survey-based study.Resuscitation plus · 2025Article
- Reconstructing Covert Consciousness: Neural Decoding as a Novel Consciousness Assessment.Neurology · 2025Review
- Seeking a Treatable Cause of Out-of-Hospital Cardiac Arrest during and after Resuscitation.Journal of clinical medicine · 2024Review
Corrections and comments
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Authors and funding
15 authors.
David FischerDivision of Neurocritical Care (DF, JML), Department of Neurology; Department of Emergency Medicine (BSA); Division of Pulmonary, Allergy and Critical Care (GDB, OJM), Department of Medicine; Department of Physical Medicine and Rehabilitation (JC, SH); Division of Epilepsy (CVK-S, SRS, GJW), Department of Neurology; Department of Palliative Care (MTM); Ethics (AMN), Perelman School of Medicine, University of Pennsylvania; Physical Therapy (WP), Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania; Clinical Resource Management and Social Work (MLS), Hospital of the University of Pennsylvania; and Division of Neuroradiology (JBW), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID https://orcid.org/0000-0001-8181-0643
Benjamin S AbellaDivision of Neurocritical Care (DF, JML), Department of Neurology; Department of Emergency Medicine (BSA); Division of Pulmonary, Allergy and Critical Care (GDB, OJM), Department of Medicine; Department of Physical Medicine and Rehabilitation (JC, SH); Division of Epilepsy (CVK-S, SRS, GJW), Department of Neurology; Department of Palliative Care (MTM); Ethics (AMN), Perelman School of Medicine, University of Pennsylvania; Physical Therapy (WP), Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania; Clinical Resource Management and Social Work (MLS), Hospital of the University of Pennsylvania; and Division of Neuroradiology (JBW), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID https://orcid.org/0000-0003-2521-0891
Geoffrey D BassDivision of Neurocritical Care (DF, JML), Department of Neurology; Department of Emergency Medicine (BSA); Division of Pulmonary, Allergy and Critical Care (GDB, OJM), Department of Medicine; Department of Physical Medicine and Rehabilitation (JC, SH); Division of Epilepsy (CVK-S, SRS, GJW), Department of Neurology; Department of Palliative Care (MTM); Ethics (AMN), Perelman School of Medicine, University of Pennsylvania; Physical Therapy (WP), Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania; Clinical Resource Management and Social Work (MLS), Hospital of the University of Pennsylvania; and Division of Neuroradiology (JBW), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID https://orcid.org/0000-0002-1893-3728
Jeremy CharlesDivision of Neurocritical Care (DF, JML), Department of Neurology; Department of Emergency Medicine (BSA); Division of Pulmonary, Allergy and Critical Care (GDB, OJM), Department of Medicine; Department of Physical Medicine and Rehabilitation (JC, SH); Division of Epilepsy (CVK-S, SRS, GJW), Department of Neurology; Department of Palliative Care (MTM); Ethics (AMN), Perelman School of Medicine, University of Pennsylvania; Physical Therapy (WP), Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania; Clinical Resource Management and Social Work (MLS), Hospital of the University of Pennsylvania; and Division of Neuroradiology (JBW), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID https://orcid.org/0009-0001-7153-2069
Stephen HamptonDivision of Neurocritical Care (DF, JML), Department of Neurology; Department of Emergency Medicine (BSA); Division of Pulmonary, Allergy and Critical Care (GDB, OJM), Department of Medicine; Department of Physical Medicine and Rehabilitation (JC, SH); Division of Epilepsy (CVK-S, SRS, GJW), Department of Neurology; Department of Palliative Care (MTM); Ethics (AMN), Perelman School of Medicine, University of Pennsylvania; Physical Therapy (WP), Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania; Clinical Resource Management and Social Work (MLS), Hospital of the University of Pennsylvania; and Division of Neuroradiology (JBW), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID https://orcid.org/0000-0003-0482-8609
Catherine V Kulick-SoperDivision of Neurocritical Care (DF, JML), Department of Neurology; Department of Emergency Medicine (BSA); Division of Pulmonary, Allergy and Critical Care (GDB, OJM), Department of Medicine; Department of Physical Medicine and Rehabilitation (JC, SH); Division of Epilepsy (CVK-S, SRS, GJW), Department of Neurology; Department of Palliative Care (MTM); Ethics (AMN), Perelman School of Medicine, University of Pennsylvania; Physical Therapy (WP), Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania; Clinical Resource Management and Social Work (MLS), Hospital of the University of Pennsylvania; and Division of Neuroradiology (JBW), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID https://orcid.org/0000-0002-8541-5912
Matthew T MendlikDivision of Neurocritical Care (DF, JML), Department of Neurology; Department of Emergency Medicine (BSA); Division of Pulmonary, Allergy and Critical Care (GDB, OJM), Department of Medicine; Department of Physical Medicine and Rehabilitation (JC, SH); Division of Epilepsy (CVK-S, SRS, GJW), Department of Neurology; Department of Palliative Care (MTM); Ethics (AMN), Perelman School of Medicine, University of Pennsylvania; Physical Therapy (WP), Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania; Clinical Resource Management and Social Work (MLS), Hospital of the University of Pennsylvania; and Division of Neuroradiology (JBW), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID https://orcid.org/0009-0003-1866-2141
Oscar J MitchellDivision of Neurocritical Care (DF, JML), Department of Neurology; Department of Emergency Medicine (BSA); Division of Pulmonary, Allergy and Critical Care (GDB, OJM), Department of Medicine; Department of Physical Medicine and Rehabilitation (JC, SH); Division of Epilepsy (CVK-S, SRS, GJW), Department of Neurology; Department of Palliative Care (MTM); Ethics (AMN), Perelman School of Medicine, University of Pennsylvania; Physical Therapy (WP), Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania; Clinical Resource Management and Social Work (MLS), Hospital of the University of Pennsylvania; and Division of Neuroradiology (JBW), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID https://orcid.org/0000-0002-5331-5562
Aliza M NarvaDivision of Neurocritical Care (DF, JML), Department of Neurology; Department of Emergency Medicine (BSA); Division of Pulmonary, Allergy and Critical Care (GDB, OJM), Department of Medicine; Department of Physical Medicine and Rehabilitation (JC, SH); Division of Epilepsy (CVK-S, SRS, GJW), Department of Neurology; Department of Palliative Care (MTM); Ethics (AMN), Perelman School of Medicine, University of Pennsylvania; Physical Therapy (WP), Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania; Clinical Resource Management and Social Work (MLS), Hospital of the University of Pennsylvania; and Division of Neuroradiology (JBW), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID https://orcid.org/0009-0008-4693-5916
William PinoDivision of Neurocritical Care (DF, JML), Department of Neurology; Department of Emergency Medicine (BSA); Division of Pulmonary, Allergy and Critical Care (GDB, OJM), Department of Medicine; Department of Physical Medicine and Rehabilitation (JC, SH); Division of Epilepsy (CVK-S, SRS, GJW), Department of Neurology; Department of Palliative Care (MTM); Ethics (AMN), Perelman School of Medicine, University of Pennsylvania; Physical Therapy (WP), Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania; Clinical Resource Management and Social Work (MLS), Hospital of the University of Pennsylvania; and Division of Neuroradiology (JBW), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID https://orcid.org/0009-0008-5098-3566
Morgan L SikandarDivision of Neurocritical Care (DF, JML), Department of Neurology; Department of Emergency Medicine (BSA); Division of Pulmonary, Allergy and Critical Care (GDB, OJM), Department of Medicine; Department of Physical Medicine and Rehabilitation (JC, SH); Division of Epilepsy (CVK-S, SRS, GJW), Department of Neurology; Department of Palliative Care (MTM); Ethics (AMN), Perelman School of Medicine, University of Pennsylvania; Physical Therapy (WP), Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania; Clinical Resource Management and Social Work (MLS), Hospital of the University of Pennsylvania; and Division of Neuroradiology (JBW), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID https://orcid.org/0009-0008-3993-1845
Saurabh R SinhaDivision of Neurocritical Care (DF, JML), Department of Neurology; Department of Emergency Medicine (BSA); Division of Pulmonary, Allergy and Critical Care (GDB, OJM), Department of Medicine; Department of Physical Medicine and Rehabilitation (JC, SH); Division of Epilepsy (CVK-S, SRS, GJW), Department of Neurology; Department of Palliative Care (MTM); Ethics (AMN), Perelman School of Medicine, University of Pennsylvania; Physical Therapy (WP), Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania; Clinical Resource Management and Social Work (MLS), Hospital of the University of Pennsylvania; and Division of Neuroradiology (JBW), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID https://orcid.org/0000-0003-0305-6731
Genna J WaldmanDivision of Neurocritical Care (DF, JML), Department of Neurology; Department of Emergency Medicine (BSA); Division of Pulmonary, Allergy and Critical Care (GDB, OJM), Department of Medicine; Department of Physical Medicine and Rehabilitation (JC, SH); Division of Epilepsy (CVK-S, SRS, GJW), Department of Neurology; Department of Palliative Care (MTM); Ethics (AMN), Perelman School of Medicine, University of Pennsylvania; Physical Therapy (WP), Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania; Clinical Resource Management and Social Work (MLS), Hospital of the University of Pennsylvania; and Division of Neuroradiology (JBW), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID https://orcid.org/0009-0002-3114-7796
Jeffrey B WareDivision of Neurocritical Care (DF, JML), Department of Neurology; Department of Emergency Medicine (BSA); Division of Pulmonary, Allergy and Critical Care (GDB, OJM), Department of Medicine; Department of Physical Medicine and Rehabilitation (JC, SH); Division of Epilepsy (CVK-S, SRS, GJW), Department of Neurology; Department of Palliative Care (MTM); Ethics (AMN), Perelman School of Medicine, University of Pennsylvania; Physical Therapy (WP), Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania; Clinical Resource Management and Social Work (MLS), Hospital of the University of Pennsylvania; and Division of Neuroradiology (JBW), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID https://orcid.org/0000-0002-3495-9733
Joshua M LevineDivision of Neurocritical Care (DF, JML), Department of Neurology; Department of Emergency Medicine (BSA); Division of Pulmonary, Allergy and Critical Care (GDB, OJM), Department of Medicine; Department of Physical Medicine and Rehabilitation (JC, SH); Division of Epilepsy (CVK-S, SRS, GJW), Department of Neurology; Department of Palliative Care (MTM); Ethics (AMN), Perelman School of Medicine, University of Pennsylvania; Physical Therapy (WP), Good Shepherd Penn Partners at the Hospital of the University of Pennsylvania; Clinical Resource Management and Social Work (MLS), Hospital of the University of Pennsylvania; and Division of Neuroradiology (JBW), Department of Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia.ORCID https://orcid.org/0000-0002-2918-4056
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Neuroprognostication for disorders of consciousness (DoC) after severe acute brain injury is a major challenge, and the conventional clinical approach struggles to keep pace with a rapidly evolving literature. Lacking specialization, and fragmented between providers, conventional neuroprognostication is variable, frequently incongruent with guidelines, and prone to error, contributing to avoidable mortality and morbidity. Recent Findings: We review the limitations of the conventional approach to neuroprognostication and DoC care, and propose a paradigm entitled the Recovery of Consciousness Via Evidence-Based Medicine and Research (RECOVER) program to address them. The aim of the RECOVER program is to provide specialized, comprehensive, and longitudinal care that synthesizes interdisciplinary perspectives, provides continuity to patients and families, and improves the future of DoC care through research and education. Implications for Practice: This model, if broadly adopted, may help establish neuroprognostication as a new subspecialty that improves the care of this vulnerable patient population.
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