Evidence map›Paper›PMID 39184693›Full record

ArticleCureus2024

A Case of Acute Human Self-Poisoning With Bispyribac Sodium Presenting as Lactic Acidosis.

Sreejith Jayachandran, Nidhi Kaeley, Parvathy Sasidharan, Joen R Mathew, Amrita Paul

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sreejith JayachandranEmergency Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Nidhi KaeleyEmergency Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Parvathy SasidharanEmergency Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Joen R MathewFamily and Community Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Amrita PaulEmergency Medicine, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case report describes a 65-year-old male who presented to the emergency department with significant lactic acidosis after self-poisoning by ingesting bispyribac sodium, a commonly known herbicide. This case highlights the rarity of poisoning with freely available herbicides in the literature, which may be elusive in clinical history and life-threatening in presentation. The patient had attempted to commit suicide with ingestion of an unidentified herbicide and was brought to the emergency department post two hours after the incident. He complained of abdominal pain. The hemodynamics of the patient were within normal limits. However, his initial lactate levels were elevated along with a high anion gap metabolic acidosis. The patient was provided symptomatic care and close monitoring. The ingested substance was later found to be bispyribac sodium. The patient symptomatically improved over time, with lactate levels attaining normal ranges, and was discharged after observation of 24 hours. Human ingestion of bispyribac sodium is mostly asymptomatic and non-fatal. The management in this case mainly consisted of symptomatic care. The initial presentation of herbicide poisoning in an emergency department setting as lactic acidosis and the subsequent evaluation to rule out other possible causes of lactic acidosis in the patient was challenging for the treating physician. The possibility of herbicide-mediated cellular damage and subsequent lactic acidosis is thought to be the reason for this rare presentation.

Indexed as

agricultural poisoningbispyribac sodiumherbicide poisinglactic acidosistoxicology

Identifiers

PMID39184693
PMCPMC11345086

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