Evidence map›Paper›PMID 39184552›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2024

Association Between Nonalcoholic Fatty Liver Disease and the Risk of Cardiovascular Disease in the Middle-Age and Elderly Population of Northern China: A Cross-Sectional Study.

Xuebing Zhang, Lianjie Wang, Ge Wang, Jiayue Li, Yiming Mu, Shidong Wang, Xiaoran Li

Abstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xuebing ZhangDepartment of Endocrinology, Dongzhimen Hospital Beijing University of Chinese Medicine, Beijing 100700, People's Republic of China.
Lianjie WangDepartment of Endocrinology, Dongzhimen Hospital Beijing University of Chinese Medicine, Beijing 100700, People's Republic of China.
Ge WangDepartment of Endocrinology, Dongzhimen Hospital Beijing University of Chinese Medicine, Beijing 100700, People's Republic of China.ORCID 0009-0006-9093-9397
Jiayue LiDepartment of Endocrinology, Dongzhimen Hospital Beijing University of Chinese Medicine, Beijing 100700, People's Republic of China.
Yiming MuDepartment of Endocrinology, First Medical Centre of Chinese PLA General Hospital, Beijing 100853, People's Republic of China.ORCID 0000-0002-3344-3540
Shidong WangDepartment of Endocrinology, Dongzhimen Hospital Beijing University of Chinese Medicine, Beijing 100700, People's Republic of China.ORCID 0009-0007-3559-6122
Xiaoran LiDepartment of Endocrinology, Dongzhimen Hospital Beijing University of Chinese Medicine, Beijing 100700, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Nonalcoholic fatty liver disease (NAFLD) has become a major global health burden, which increases the risk of extra-hepatic complications such as type 2 diabetes mellitus (T2DM), dyslipidemia, metabolic syndrome (MetS), and cardiovascular disease (CVD). However, NAFLD remains underappreciated and underdiagnosed. Our study aimed to explore the prevalence of NAFLD and the association between NAFLD and CVD events among adults aged 40 and older in Northern China. Methods: This study was conducted in the Shijingshan district of Beijing, China from November 2011 to August 2012. A total of 18891 subjects were recruited in the study. The information including demographical information, lifestyle, previous history of diabetes, hypertension, dyslipidemia, CVD, and liver disease were gathered. Data on physical examination, blood lipid profile, fasting blood glucose, and 2-hour blood glucose were recorded. Determination of MetS was according to T2DM guideline of Chinese Diabetes Society (2020 edition). The association between CVD and NAFLD was evaluated by multivariate logistic regression. Results: The prevalence of NAFLD was 15.2%. After adjustment for age, smoking status, alcohol intake, WC, hypertension, dyslipidemia and hyperglycemia, the odds ratios (ORs) of CVD in men were 1.622 (95%CI: 1.345-1.957) and 1.990 (95%CI: 1.709-2.316) in women with NAFLD, compared with the subjects without NAFLD. Conclusions: NAFLD is independently associated with increased risk of CVD development.

Indexed as

cardiovascular diseaseChinesemetabolic syndromemiddle-aged and elderlynonalcoholic fatty liver disease

Identifiers

PMID39184552
PMCPMC11345005

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.