Evidence map›Paper›PMID 39184231›Full record

ArticleIn silico pharmacology2024

Antibacterial activity of natural flavones against bovine mastitis pathogens: in vitro, SAR analysis, and computational study.

Ahlam Haj Hasan, Gagan Preet, Rishi Vachaspathy Astakala, Hanan Al-Adilah, Emmanuel Tope Oluwabusola, Rainer Ebel, Marcel Jaspars

Abstract read
In one paragraph

Article in In silico pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ahlam Haj HasanDepartment of Chemistry, Marine Biodiscovery Centre, University of Aberdeen, Aberdeen, AB24 3UE UK.
Gagan PreetDepartment of Chemistry, Marine Biodiscovery Centre, University of Aberdeen, Aberdeen, AB24 3UE UK.
Rishi Vachaspathy AstakalaDepartment of Chemistry, Marine Biodiscovery Centre, University of Aberdeen, Aberdeen, AB24 3UE UK.
Hanan Al-AdilahEnvironment and Life Sciences Research Centre, Kuwait Institute for Scientific Research, P.O. Box 24885, Safat, 13109 Kuwait.
Emmanuel Tope OluwabusolaDepartment of Chemistry, Marine Biodiscovery Centre, University of Aberdeen, Aberdeen, AB24 3UE UK.
Rainer EbelDepartment of Chemistry, Marine Biodiscovery Centre, University of Aberdeen, Aberdeen, AB24 3UE UK.
Marcel JasparsDepartment of Chemistry, Marine Biodiscovery Centre, University of Aberdeen, Aberdeen, AB24 3UE UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bovine mastitis is a worldwide disease affecting dairy cattle and causes major economic losses in the dairy industry. Recently, the emergence of microbial resistance to the current antibiotics complicates the treatment protocol which necessitates antibiotic stewardship and further research to find new active compounds. Recently, phytobiotics have gained interest in being used as an alternative to antibiotics in the poultry industry as an antibiotic stewardship intervention. This study evaluated the in vitro antibacterial activity of 16 flavonoids against bovine mastitis pathogens. Two flavones: 2-(4-methoxyphenyl)chromen-4-one ( Supplementary Information: The online version contains supplementary material available at 10.1007/s40203-024-00253-w.

Indexed as

Bovine mastitisFlavonoidsIn vitroMolecular dockingPharmacophoreStructure-activity relationship

Identifiers

PMID39184231
PMCPMC11344746

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.