Evidence map›Paper›PMID 39184171›Full record

ArticleEuropean heart journal. Case reports2024

Severe hypotension requiring resuscitation in tumour-related carotid sinus syndrome: a case report.

Martijn G Klingenberg, Steef J Sinkeler, Niels Koopmans, Robin E Plaat

Abstract readCase Reports
In one paragraph

Article in European heart journal. Case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Martijn G KlingenbergDepartment of Cardiology, Medisch Centrum Leeuwarden, Henti Dunantlaan 2, Leeuwarden 8934 AD, Netherlands.ORCID https://orcid.org/0009-0009-5845-3225
Steef J SinkelerDepartment of Cardiology, Medisch Centrum Leeuwarden, Henti Dunantlaan 2, Leeuwarden 8934 AD, Netherlands.
Niels KoopmansDepartment of Cardiology, Medisch Centrum Leeuwarden, Henti Dunantlaan 2, Leeuwarden 8934 AD, Netherlands.
Robin E PlaatDepartment of Cardiology, Medisch Centrum Leeuwarden, Henti Dunantlaan 2, Leeuwarden 8934 AD, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: An uncommon cause of reflex syncope is carotid sinus syndrome (CSS). In rare cases, this can be caused by compression of the carotid sinus by a progressive or invasive tumour. Case summary: A 57-year-old female was presented at the emergency department with recurrent syncope in the morning. After initial observation, no heart rhythm abnormalities or syncope were observed. The day after discharge, she was presented again with a syncope. Hypotension and bradycardia were observed this time. Furthermore, a mass in the neck area was found near the carotid artery. She was admitted to the cardiology department with suspected carotid sinus syndrome for telemetric observation. Diagnostics by biopsy and PET-CT showed a metastasized squamous cell carcinoma of the tongue. Initial treatment of dexamethasone was started after which the recurrence of the syncope decreased. However, during admission, an in-hospital cardiac arrest occurred due to persistent vagal stimulation. As a result, the patient was started on neoadjuvant chemotherapy and midodrine, after which she experienced multiple complications and died. Discussion: To the best of our knowledge, this is the first case report that shows an IHCA due to severe hypotension related to a carotid sinus syndrome.

Indexed as

Carotid sinus syndromeCase reportIn-hospital cardiac arrestMidodrineOropharyngeal tumour

Identifiers

PMID39184171
PMCPMC11342958

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.