Evidence map›Paper›PMID 39184158›Full record

ReviewMethodist DeBakey cardiovascular journal2024

Myocardial Recovery in Cardiogenic Shock.

Kevin John, Adnan Khalif, Masaki Tsukashita, Manreet K Kanwar

Abstract readReview
In one paragraph

Review in Methodist DeBakey cardiovascular journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Kevin JohnTufts Medical Center, Boston, Massachusetts, US.ORCID https://orcid.org/0000-0003-3382-0294
Adnan KhalifCardiovascular Institute at Allegheny Health Network, Pittsburgh, Pennsylvania, US.ORCID https://orcid.org/0000-0002-8235-4253
Masaki TsukashitaCardiovascular Institute at Allegheny Health Network, Pittsburgh, Pennsylvania, US.ORCID https://orcid.org/0000-0001-9387-4759
Manreet K KanwarCardiovascular Institute at Allegheny Health Network, Pittsburgh, Pennsylvania, US.ORCID https://orcid.org/0000-0002-7280-5268

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The overarching goal of cardiogenic shock (CS) therapy is ensuring long-term survival. In recent years, increasing emphasis has been placed on analyzing mechanisms to improve outcomes in CS. This includes averting in-hospital mortality, modifying the disease process by promoting heart recovery while avoiding multiorgan failure, and circumventing complications related to both CS and treatment strategies deployed to treat CS. Heart replacement therapies represent a viable strategy for long-term survival but are restricted to a small, select percentage of patients. In this review we focus on pathophysiology of the shock state, with an emphasis on addressing reversible etiologies contributing to the decompensated state, optimizing physiological factors for recovery, and identifying therapeutic targets to promote recovery. We also review the known predictors of myocardial recovery, regardless of the etiology of CS. Lastly, we highlight the current gaps in knowledge in this field and support additional high-quality studies focusing on myocardial recovery in CS.

Indexed as

Recovery of FunctionShock, CardiogenicAnimalsHumansRisk FactorsTime FactorsTreatment OutcomeVentricular Function, Leftcardiogenic shockguideline-directed medical therapymechanical circulatory supportmyocardial recovery

Identifiers

PMID39184158
PMCPMC11342837

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.