Evidence map›Paper›PMID 39184022›Full record

ArticleMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention2023

Relaxation-Diffusion Spectrum Imaging for Probing Tissue Microarchitecture.

Ye Wu, Xiaoming Liu, Xinyuan Zhang, Khoi Minh Huynh, Sahar Ahmad, Pew-Thian Yap

Abstract read
In one paragraph

Article in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ye WuSchool of Computer Science and Engineering, Nanjing University of Science and Technology, Nanjing, China.
Xiaoming LiuUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Xinyuan ZhangSchool of Biomedical Engineering, Southern Medical University, Guangzhou, China.
Khoi Minh HuynhDepartment of Radiology, University of North Carolina, Chapel Hill, NC, USA.
Sahar AhmadDepartment of Radiology, University of North Carolina, Chapel Hill, NC, USA.
Pew-Thian YapDepartment of Radiology, University of North Carolina, Chapel Hill, NC, USA.

Funding

Longitudinal Mapping of Human Brain Development in the First Years of LifeR01EB008374 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2009 to 2024
$5.1M
Computational Diffusion MRI for Studying Early Human Brain DevelopmentR01MH125479 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2021 to 2025
$2.1M
Comprehensive MR Fingerprinting for Infants and Young Children at Risk for Developmental Delays.R01HD112923 · NICHD · DUKE UNIVERSITY · PI Dan Ma, DEANNE E WILSON-COSTELLO · 2024 to 2026
$1.7M
NIBIB NIH HHS R01 EB008374NICHD NIH HHS R01 HD112923NIMH NIH HHS R01 MH125479
6 · The paper itself

Abstract

Brain tissue microarchitecture is characterized by heterogeneous degrees of diffusivity and rates of transverse relaxation. Unlike standard diffusion MRI with a single echo time (TE), which provides information primarily on diffusivity, relaxation-diffusion MRI involves multiple TEs and multiple diffusion-weighting strengths for probing tissue-specific coupling between relaxation and diffusivity. Here, we introduce a relaxation-diffusion model that characterizes tissue apparent relaxation coefficients for a spectrum of diffusion length scales and at the same time factors out the effects of intra-voxel orientation heterogeneity. We examined the model with an in vivo dataset, acquired using a clinical scanner, involving different health conditions. Experimental results indicate that our model caters to heterogeneous tissue microstructure and can distinguish fiber bundles with similar diffusivities but different relaxation rates. Code with sample data is available at https://github.com/dryewu/RDSI.

Indexed as

Diffusion MRIMicrostructureRelaxation diffusion

Identifiers

PMID39184022
PMCPMC11340880

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.