Evidence map›Paper›PMID 39183645›Full record

ArticleNMR in biomedicine2024

Free-breathing time-resolved 4D MRI with improved T1-weighting contrast.

Jingjia Chen, Ding Xia, Chenchan Huang, Krishna Shanbhogue, Hersh Chandarana, Li Feng

Abstract read
In one paragraph

Article in NMR in biomedicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jingjia ChenBernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0000-0002-6023-1033
Ding XiaIcahn School of Medicine at Mount Sinai, Biomedical Engineering and Imaging Institute, New York, New York, USA.
Chenchan HuangBernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, New York, USA.
Krishna ShanbhogueBernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, New York, USA.
Hersh ChandaranaBernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, New York, USA.
Li FengBernard and Irene Schwartz Center for Biomedical Imaging, Department of Radiology, New York University Grossman School of Medicine, New York, New York, USA.ORCID 0000-0002-8692-7645

Funding

TR&D 4: Revealing Microstructure: Biophysical modeling and validation for discovery and clinical careP41EB017183 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Christopher M Collins · 2014 to 2026
$19.3M
Rapid Motion-Robust and Easy-to-Use Dynamic Contrast-Enhanced MRI for Liver Perfusion QuantificationR01EB030549 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FENG, LI · 2021 to 2024
$1.7M
Rapid Structure-Function MRI of the Lung for Post-COVID-19 ManagementR01EB031083 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FENG, LI · 2021 to 2021
$1.5M
3D Free-Breathing Fat and Iron Corrected T1 MappingR21EB032917 · NIBIB · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FENG, LI · 2022 to 2023
$465k
National Institutes of Health (NIH) P41EB017183National Institutes of Health (NIH) R01EB030549National Institutes of Health (NIH) R01EB031083NIBIB NIH HHS P41 EB017183NIBIB NIH HHS R01 EB030549NIBIB NIH HHS R01 EB031083NIBIB NIH HHS R21 EB032917
6 · The paper itself

Abstract

This work proposes MP-Grasp4D (magnetization-prepared golden-angle radial sparse parallel 4D) MRI, a free-breathing, inversion recovery (IR)-prepared, time-resolved 4D MRI technique with improved T1-weighted contrast. MP-Grasp4D MRI acquisition incorporates IR preparation into a radial gradient echo sequence. MP-Grasp4D employs a golden-angle navi-stack-of-stars sampling scheme, where imaging data of rotating radial stacks and navigator stacks (acquired at a consistent rotation angle) are alternately acquired. The navigator stacks are used to estimate a temporal basis for low-rank subspace-constrained reconstruction. This allows for the simultaneous capture of both IR-induced contrast changes and respiratory motion. One temporal frame of the imaging volume in MP-Grasp4D MRI is reconstructed from a single stack and an adjacent navigator stack on average, resulting in a nominal temporal resolution of 0.16 seconds per volume. Images corresponding to the optimal inversion time (TI) can be retrospectively selected for providing the best image contrast. Reader studies were conducted to assess the performance of MP-Grasp4D MRI in liver imaging across 30 subjects in comparison with standard Grasp4D MRI without IR preparation. MP-Grasp4D MRI received significantly higher scores (P < 0.05) than Grasp4D in all assessment categories. There was a moderate to almost perfect agreement (kappa coefficient from 0.42 to 0.9) between the two readers for image quality assessment. When the scan time is reduced, MP-Grasp4D MRI preserves image contrast and quality, demonstrating additional acceleration capability. MP-Grasp4D MRI improves T1-weighted contrast for free-breathing time-resolved 4D MRI and eliminates the need for explicit motion compensation. This method is expected to be valuable in different MRI applications such as MR-guided radiotherapy.

Indexed as

Magnetic Resonance ImagingRespirationAdultFemaleHumansImaging, Three-DimensionalLiverMaleTime Factors4D MRIGRASPMP‐GRASPMP‐Grasp4Dnavi‐stack‐of‐starstime‐resolved

Identifiers

PMID39183645
PMCPMC12063541

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.