Evidence map›Paper›PMID 39183508›Full record

ArticleBioelectromagnetics2025

Stimulus effects of extremely low-frequency electric field exposure on calcium oscillations in a human cortical spheroid.

Atsushi Saito, Takeo Shiina, Yoichi Sekiba

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioelectromagnetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Atsushi SaitoSustainable System Research Laboratory, Biology and Environmental Chemistry Division, Central Research Institute of Electric Power Industry (CRIEPI), Abiko, Japan.ORCID http://orcid.org/0000-0001-8010-152X
Takeo ShiinaGrid Innovation Research Laboratory, Electric Facility Technology Division, Central Research Institute of Electric Power Industry (CRIEPI), Yokosuka, Japan.ORCID https://orcid.org/0000-0003-4921-7051
Yoichi SekibaPower System Analysis Group, Denryoku Computing Center (DCC), Komae, Japan.ORCID https://orcid.org/0000-0001-7688-2052

Funding

Japan Society for the Promotion of Science JP23K25185
6 · The paper itself

Abstract

High-intensity, low-frequency (1 Hz to 100 kHz) electric and magnetic fields (EF and MF) cause electrical excitation of the nervous system via an induced EF (iEF) in living tissue. However, the biological properties and thresholds of stimulus effects on synchronized activity in a three-dimensional (3D) neuronal network remain uncertain. In this study, we evaluated changes in neuronal network activity during extremely low-frequency EF (ELF-EF) exposure by measuring intracellular calcium ([Ca

Indexed as

Calcium SignalingCerebral CortexSpheroids, CellularCalciumElectricityElectromagnetic FieldsHumansInduced Pluripotent Stem CellsNeuronsCalciumelectric fieldhuman cortical spheroidlow‐frequencynerve stimulationneuronal activity

Identifiers

PMID39183508
PMCPMC11650428

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.