Evidence map›Paper›PMID 39183324›Full record

ArticleNature communications2024

An essential role for the latero-medial secondary visual cortex in the acquisition and retention of visual perceptual learning in mice.

Alan Consorti, Gabriele Sansevero, Irene Di Marco, Silvia Floridia, Elena Novelli, Nicoletta Berardi, Alessandro Sale

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alan Consorti *Neuroscience Institute, National Research Council (CNR), Pisa, Italy.ORCID 0000-0002-4586-8239
Gabriele Sansevero *Neuroscience Institute, National Research Council (CNR), Pisa, Italy.ORCID 0000-0003-0562-5459
Irene Di MarcoNeuroscience Institute, National Research Council (CNR), Pisa, Italy.
Silvia FloridiaNeuroscience Institute, National Research Council (CNR), Pisa, Italy.ORCID 0009-0008-3976-5082
Elena NovelliNeuroscience Institute, National Research Council (CNR), Pisa, Italy.
Nicoletta BerardiNeuroscience Institute, National Research Council (CNR), Pisa, Italy.
Alessandro SaleNeuroscience Institute, National Research Council (CNR), Pisa, Italy. sale@in.cnr.it.ORCID 0000-0001-7608-4456

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perceptual learning refers to any change in discrimination abilities as a result of practice, a fundamental process that improves the organism's response to the external environment. Visual perceptual learning (vPL) is supposed to rely on functional rearrangements in brain circuity occurring at early stages of sensory processing, with a pivotal role for the primary visual cortex (V1). However, top-down inputs from higher-order visual areas (HVAs) have been suggested to play a key part in vPL, conveying information on attention, expectation and the precise nature of the perceptual task. A direct assessment of the possibility to modulate vPL by manipulating top-down activity in awake subjects is still missing. Here, we used a combination of chemogenetics, behavioral analysis and multichannel electrophysiological assessments to show a critical role in vPL acquisition and retention for neuronal activity in the latero-medial secondary visual cortex (LM), the prime source for top-down feedback projections reentering V1.

Indexed as

LearningVisual CortexVisual PerceptionAnimalsFemaleMaleMiceMice, Inbred C57BLNeuronsPhotic StimulationPrimary Visual Cortex

Identifiers

PMID39183324
PMCPMC11345418

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.