Evidence map›Paper›PMID 39183238›Full record

ArticleScientific reports2024

MgO-enhanced β-TCP promotes osteogenesis in both in vitro and in vivo rat models.

Kenichiro Saito, Yusuke Inagaki, Yoshinobu Uchihara, Masakazu Okamoto, Yuki Nishimura, Akihito Kawai, Tatsuro Sugino, Kensuke Okamura, Munehiro Ogawa, Akira Kido and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Kenichiro SaitoDepartment of Orthopedic Surgery, Nara Medical University, Kashihara, Nara, Japan.
Yusuke InagakiDepartment of Rehabilitation Medicine, Nara Medical University, Kashihara, Nara, Japan. yinagaki@naramed-u.ac.jp.
Yoshinobu UchiharaDepartment of Orthopedic Surgery, Nara Medical University, Kashihara, Nara, Japan.
Masakazu OkamotoDepartment of Orthopedic Surgery, Nara Medical University, Kashihara, Nara, Japan.
Yuki NishimuraDepartment of Orthopedic Surgery, Nara Medical University, Kashihara, Nara, Japan.
Akihito KawaiDepartment of Orthopedic Surgery, Nara Medical University, Kashihara, Nara, Japan.
Tatsuro SuginoProduct Development Department, Olympus Terumo Biomaterials Corp., Shizuoka, Japan.
Kensuke OkamuraDepartment of Orthopedic Surgery, Nara Medical University, Kashihara, Nara, Japan.
Munehiro OgawaDepartment of Sports Medicine, Nara Medical University, Kashihara, Nara, Japan.
Akira KidoDepartment of Rehabilitation Medicine, Nara Medical University, Kashihara, Nara, Japan.
Yasuhito TanakaDepartment of Orthopedic Surgery, Nara Medical University, Kashihara, Nara, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allogeneic bone grafts are used to treat bone defects in orthopedic surgery, but the osteogenic potential of artificial bones remains a challenge. In this study, we developed a β-tricalcium phosphate (β-TCP) formulation containing MgO, ZnO, SrO, and SiO

Indexed as

Calcium PhosphatesMagnesium OxideMesenchymal Stem CellsOsteogenesisTissue ScaffoldsAlkaline PhosphataseAnimalsBone Morphogenetic Protein 2Cell DifferentiationCells, CulturedMaleRatsRats, Sprague-DawleyTissue EngineeringVascular Endothelial Growth Factor AX-Ray MicrotomographyAlkaline Phosphatasebeta-tricalcium phosphateBone Morphogenetic Protein 2Calcium PhosphatesMagnesium OxideVascular Endothelial Growth Factor AAllogeneic bone graftsBone marrow-derived mesenchymal stem cells osteogenesisβ-tricalcium phosphate

Identifiers

PMID39183238
PMCPMC11345426

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.