ArticleBMC urology2024
Association between the atherogenic index of plasma and kidney stones: a nationally representative study.
Article in BMC urology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Composite metabolic indices and calcium oxalate stone formation: a multicenter comparative study of HOMA-IR, PAI, TyG, and METS-IR.International urology and nephrology · 2026Article
- The atherogenic index of plasma increases the risk of incident kidney stones: a nested case-control study in Chinese adults.Renal failure · 2025Article
- Correlation between atherogenic index of plasma and retinal vessels in the fundus: a cross-sectional study.European journal of medical research · 2025Article
- Inverted V-shaped association between atherogenic index of plasma and kidney stone risk: results from NHANES 2011-2018.Translational andrology and urology · 2025Article
- BRI is an independent predictor of new-onset kidney stones in a non-diabetic population: a retrospective analysis.Frontiers in endocrinology · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
purposeThe atherogenic index of plasma (AIP) is a novel comprehensive lipid index. We aimed to investigate a possible relationship between AIP index and kidney stones in US adults.
methodsThis cross-sectional study was conducted among adults with complete AIP index and questionnaire records on kidney stones from the National Health and Nutrition Examination Survey (NHANES) spanning from 2007 to 2018. The AIP index served as the exposure variable, defined as the logarithm of the ratio between triglycerides (TG, mmol/L) and high-density lipoprotein cholesterol (HDL-c, mmol/L). Self-reported history of kidney stones was utilized as the outcome variable. The independent relationship between AIP index and the risk of kidney stones was fully assessed.
resultsA total of 14,833 participants were included in this study, with an average AIP index of -0.07 ± 0.01. The proportion of kidney stones progressively increased with higher AIP index tertile intervals (7.33% vs. 9.97% vs. 12.57%, P < 0.001). Furthermore, AIP index was found to be independently associated with the risk of kidney stones after adjusting for confounding factors (OR = 1.32, 95% CI 1.08-1.61, P = 0.006). Restricted cubic spline (RCS) analysis confirmed the robustness of our results. There was no significant interaction observed based on subgroup analysis stratified by age, gender, race, body mass index (BMI, kg/m
conclusionsThe AIP index may be a potential epidemiological tool to quantify the role of dyslipidemia in the risk of kidney stones in US adults.
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