Evidence map›Paper›PMID 39181716›Full record

ArticleInternational journal of spine surgery2024

Predictability in Achieving Target Intervertebral Lordosis Using Personalized Interbody Implants.

Saeed S Sadrameli, Donald J Blaskiewicz, Jahangir Asghar, Christopher P Ames, Gregory M Mundis, Joseph A Osorio, Justin S Smith, Chun-Po Yen, Sigurd H Berven, Ashvin I Patel and 3 more

Abstract read
In one paragraph

Article in International journal of spine surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Successful execution of preoperative lumbar alignment planning: reliability of the L5-S1 anterior lumbar interbody fusion (ALIF).European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Saeed S SadrameliAdventHealth Celebration, Celebration, FL, USA Dr.Sadrameli@orlandoneurosurgery.com.
Donald J BlaskiewiczSt. Luke's Boise Medical Center, Boise, ID, USA.
Jahangir AsgharElite Spine Health and Wellness, Plantation, FL, USA.
Christopher P AmesDepartment of Neurological Surgery, University of California, San Francisco, CA, USA.
Gregory M MundisDepartment of Orthopedic Surgery, Scripps Clinic, La Jolla, CA, USA.
Joseph A OsorioDepartment of Neurological Surgery, University of California, San Diego, CA, USA.
Justin S SmithDepartment of Neurosurgery, University of Virginia, Charlottesville, VA, USA.
Chun-Po YenDepartment of Neurosurgery, University of Virginia, Charlottesville, VA, USA.
Sigurd H BervenDepartment of Orthopedic Surgery, University of California, San Francisco, CA, USA.
Ashvin I PatelKennedy-White Orthopedic Center, Sarasota, FL, USA.
Michele Temple-WongCarlsmed, Carlsbad, CA, USA.
Rodrigo J NicolauCarlsmed, Carlsbad, CA, USA.
Roland S KentAxis Spine Center, Coeur d'Alene, ID, USA.

Funding

Skeletal Biology and Biomechanics (SBB) CoreP30AR075055 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI EDWARD C HSIAO · 2019 to 2026
$7.1M
NIAMS NIH HHS P30 AR075055
6 · The paper itself

Abstract

backgroundLumbar lordosis distribution has become a pivotal factor in re-establishing the foundational alignment of the lumbar spine. This can directly influence overall sagittal alignment, leading to improved long-term outcomes for patients. Despite the wide availability of hyperlordotic stock cages intended to achieve optimal postoperative alignment, there is a lack of correlation between the lordotic shape of a cage and the resultant intervertebral alignment. Recently, personalized spine surgery has witnessed significant advancements, including 3D-printed personalized interbody implants, which are customized to the surgeon's treatment and alignment goals. This study evaluates the reliability of 3D-printed patient-specific interbody implants to achieve the planned postoperative intervertebral alignment.

methodsThis is a retrospective study of 217 patients with spinal deformity or degenerative conditions. Patients were included if they received 3D-printed personalized interbody implants. The desired intervertebral lordosis (IVL) angle was prescribed into the device design for each personalized interbody (IVL goal). Standing postoperative radiographs were measured, and the IVL offset was calculated as IVL achieved minus IVL goal.

resultsIn this patient population, 365 personalized interbodies were implanted, including 145 anterior lumbar interbody fusions (ALIFs), 99 lateral lumbar interbody fusions (LLIFs), and 121 transforaminal lumbar interbody fusions. Among the 365 treated levels, IVL offset was 1.1° ± 4.4° (mean ± SD). IVL was achieved within 5° of the plan in 299 levels (81.9%). IVL offset depended on the approach of the lumbar interbody fusion and was achieved within 5° for 85.9% of LLIF, 82.6% of transforaminal lumbar interbody fusions and 78.6% of ALIFs. Ten levels (2.7%) missed the planned IVL by >10°. ALIF and LLIF levels in which the plan was missed by more than 5° tended to be overcorrected.

conclusionsThis study supports the use of 3D-printed personalized interbody implants to achieve planned sagittal intervertebral alignment. CLINICAL RELEVANCE: Personalized interbody implants can consistently achieve IVL goals and potentially impact foundational lumbar alignment. LEVEL OF EVIDENCE: 4:

Indexed as

cagedeviceinterbodyintervertebrallordosislumbar fusionpersonalizedpre-operative planning

Identifiers

PMID39181716
PMCPMC11483450

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.