ArticleCEN case reports2025
Recurrent acute kidney injury with Fanconi syndrome related to red yeast rice supplement.
Article in CEN case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- A 28-day subacute toxicity study of puberulic acid in Crl:CD(SD) rats.Journal of toxicologic pathology · 2025Article
- Successful Resolution of Suspected Red Yeast Rice-induced Nephropathy.Internal medicine (Tokyo, Japan) · 2025Article
- Subclinical acute tubular necrosis potentially associated with red yeast rice consumption unexpectedly detected in a patient with membranous nephropathy.CEN case reports · 2025Article
- Two Cases of Chronic Tubular Necrosis Presenting as Fanconi Syndrome Induced by Red Yeast Rice Choleste-Help.Diagnostics (Basel, Switzerland) · 2025Article
- Tubular damage and SGLT2 expression in a patient with Beni-koji tablet-associated acute kidney injury and Fanconi syndrome.CEN case reports · 2025Article
- Review
- Tubular glycogen accumulation in acute kidney injury associated with red yeast rice supplement.Clinical kidney journal · 2024Article
- Approach to Renal Tubular Acidosis - A Review.Indian journal of endocrinology and metabolismReview
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Authors and funding
6 authors.
Funding
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Abstract
A 51-year-old woman was admitted to our hospital for acute kidney injury (AKI) with an elevated serum creatinine level of 5.07 mg/dL and Fanconi syndrome. The patient was discharged after partial recovery of kidney dysfunction with conservative treatment but was readmitted approximately three months later due to a recurrence of AKI with Fanconi syndrome. A kidney biopsy revealed findings consistent with acute tubular necrosis and localized tubulointerstitial nephritis, with no specific vascular or glomerular lesions. The patient's medical history revealed that prior to both AKI episodes, the patient had been taking "Red Yeast Cholestehelp", a lipid-lowering supplement for a period of time. Her kidney dysfunction and Fanconi syndrome improved with the discontinuation of the supplement and correction with oral medications. In Japan, a series of similar health hazards related to the red yeast rice supplement has been reported, but the causative toxin and its causal relationship with AKI have not been established. The present case provides firm evidence that clinically supports this relationship.
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