Evidence map›Paper›PMID 39180440›Full record

ArticleThe Laryngoscope2025

Quality-of-Life Outcomes Following Endoscopic Resection of Sinonasal Inverted Papilloma.

Arash Abiri, Ellen M Hong, Katelyn K Dilley, Theodore V Nguyen, Mandy K Salmon, Elysia M Grose, Siddhant H Tripathi, Sanjena Venkatesh, Yohan Kim, Daniel J Lee and 10 more

Abstract readMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in The Laryngoscope, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Arash AbiriDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California, U.S.A.ORCID 0000-0003-2656-1060
Ellen M HongDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California, U.S.A.
Katelyn K DilleyDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California, U.S.A.ORCID 0000-0002-3034-5662
Theodore V NguyenDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California, U.S.A.ORCID 0000-0002-3416-5976
Mandy K SalmonDepartment of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.
Elysia M GroseDepartment of Otolaryngology-Head and Neck Surgery, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-3054-3474
Siddhant H TripathiDepartment of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, U.S.A.ORCID 0000-0001-7957-3802
Sanjena VenkateshDepartment of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.ORCID 0009-0009-4051-9994
Yohan KimDepartment of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.
Daniel J LeeDepartment of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.
Jennifer E DouglasDepartment of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.ORCID 0000-0002-3634-2067
Jacob G EideDepartment of Otolaryngology-Head and Neck Surgery, Henry Ford Health System, Detroit, Michigan, U.S.A.ORCID 0000-0003-3727-8287
Rijul S KshirsagarDepartment of Head and Neck Surgery, Kaiser Permanente Redwood City Medical Center, Redwood City, California, U.S.A.ORCID 0000-0002-3113-2685
Katie M PhillipsDepartment of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, U.S.A.
Ahmad R SedaghatDepartment of Otolaryngology-Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, U.S.A.ORCID 0000-0001-6331-2325
John M LeeDepartment of Otolaryngology-Head and Neck Surgery, University of Toronto, Toronto, Ontario, Canada.
Charles C L TongDepartment of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.ORCID 0000-0002-4471-5134
Nithin D AdappaDepartment of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.
James N PalmerDepartment of Otorhinolaryngology-Head and Neck Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, U.S.A.
Edward C KuanDepartment of Otolaryngology-Head and Neck Surgery, University of California, Irvine, California, U.S.A.ORCID 0000-0003-3475-0718

Funding

MEDICAL SCIENTIST TRAINING PROGRAMT32GM008620 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI GOLDIN, ALAN L · 1999 to 2023
$8.1M
NIGMS NIH HHS T32 GM008620NIGMS NIH HHS T32GM008620
6 · The paper itself

Abstract

objectivesThere is growing interest in assessing patient quality of life (QOL) following treatment of sinonasal tumors, including inverted papilloma (IP). We aimed to elucidate the natural history of postoperative QOL outcomes in IP patients treated with surgery.

methodsCases of sinonasal IP treated surgically at 4 tertiary academic rhinology centers were retrospectively reviewed. SNOT-22 scores were used to evaluate QOL preoperatively and postoperatively (1, 3, 6, 12 months). Repeated-measures ANOVA assessed for differences in mean scores over time. Linear regression identified factors associated with QOL longitudinally.

results373 patients were analyzed. Mean preoperative SNOT-22 score was 20.6 ± 20.4, which decreased to 16.3 ± 18.8 (p = 0.041) and 11.8 ± 15.0 (p < 0.001) at 1 and 3 months postoperatively, respectively. No further changes in SNOT-22 scores occurred beyond 3 months postoperatively (p > 0.05). When analyzed by SNOT-22 subdomains, nasal, sleep, and otologic/facial subdomain scores (all p < 0.05) demonstrated improvement at 12-month follow-up compared with preoperative scores; this was not observed for the emotional subdomain score (p = 0.800). Recurrent cases were associated with higher long-term SNOT-22 scores (β = 7.08; p = 0.017). Age, sex, degree of dysplasia, prior surgery, primary site, and smoking history did not correlate with symptoms (all p > 0.05).

conclusionsQOL outcomes related to IP resection are largely driven by nasal, sleep, and otologic/facial subdomains, though patients appear to experience enduring improvement as early as 3 months postoperatively. Recurrent disease is a major driver of negative QOL. LEVEL OF EVIDENCE: 4 Laryngoscope, 135:579-585, 2025.

Indexed as

EndoscopyPapilloma, InvertedParanasal Sinus NeoplasmsQuality of LifeAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTreatment Outcomeendoscopic surgeryinverted papillomaquality of lifeSchneiderian cell papilloma

Identifiers

PMID39180440
PMCPMC11725692

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.