Evidence map›Paper›PMID 39180295›Full record

ArticleThe Journal of international medical research2024

Assessment of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio and systemic immune-inflammatory index, as diagnostic markers for neonatal sepsis.

Shanshan Zhu, Qian Zhou, Zhonghua Hu, Junsheng Jiang

Abstract read
In one paragraph

Article in The Journal of international medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shanshan ZhuDepartment of Pediatrics, The First People's Hospital of Linping District, Hangzhou, China.
Qian ZhouDepartment of Emergency, The Second Affiliated Hospital Of Zhejiang University, Hangzhou, China.
Zhonghua HuDepartment of Pediatrics, The First People's Hospital of Linping District, Hangzhou, China.
Junsheng JiangDepartment of Pediatrics, The First People's Hospital of Linping District, Hangzhou, China.ORCID 0000-0002-1521-9414

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo assess the neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) and systemic immune-inflammatory index (SII), as diagnostic markers for neonatal sepsis.

methodsThis retrospective study involve neonates with sepsis and healthy neonates as controls. NLR, PLR, and SII were compared between groups.

resultIn total, 60 neonates with sepsis and 60 healthy controls were involved in the study. Compared with controls, the sepsis group had higher values for NLR, PLR and SII. Logistic regression analysis suggested that the NLR, PLR and SII were independent risk factors for neonatal sepsis. In addition, receiver operating characteristic (ROC) curve analysis indicated that the NLR, PLR and SII were reliable predictors of neonatal sepsis and SII had the best predictive value.

conclusionsNLR, PLR and SII appear to be useful indicators for predicting neonatal sepsis.

Indexed as

BiomarkersBlood PlateletsLymphocytesNeonatal SepsisNeutrophilsROC CurveCase-Control StudiesFemaleHumansInfant, NewbornInflammationLymphocyte CountMalePlatelet CountRetrospective StudiesRisk FactorsBiomarkersneonatal sepsisneutrophil to lymphocyte ratioplatelet to lymphocyte ratioSystemic immune-inflammatory index

Identifiers

PMID39180295
PMCPMC11344890

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.