Evidence map›Paper›PMID 39180294›Full record

ArticleThe Journal of international medical research2024

Dapagliflozin-induced abnormal uterine bleeding in a patient with dilated cardiomyopathy and chronic heart failure: a case report.

Shikun Gong, Shunan Zhang, Yun Ye, Meiling Wu

Abstract readCase Reports
In one paragraph

Article in The Journal of international medical research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shikun GongDepartment of Cardiovascular, Beilun District People's Hospital (Zhejiang University School of Medicine First Affiliated Hospital Beilun Branch), Ningbo, Zhejiang 315800, China.
Shunan ZhangDepartment of Cardiovascular, Beilun District People's Hospital (Zhejiang University School of Medicine First Affiliated Hospital Beilun Branch), Ningbo, Zhejiang 315800, China.
Yun YeDepartment of Pharmacy, Beilun District People's Hospital (Zhejiang University School of Medicine First Affiliated Hospital Beilun Branch), Ningbo, Zhejiang 315800, China.ORCID 0000-0001-8134-5657
Meiling WuDepartment of Pharmacy, Beilun District People's Hospital (Zhejiang University School of Medicine First Affiliated Hospital Beilun Branch), Ningbo, Zhejiang 315800, China.ORCID 0000-0001-9549-9729

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium-glucose cotransporter-2 (SGLT2) inhibitors are extensively used in the management of heart failure because of their cardiovascular benefits. Adverse drug reactions associated with dapagliflozin include diabetic ketoacidosis, fungal infections, and increased blood glucose concentrations. However, abnormal uterine bleeding is not a known side effect of dapagliflozin. We report a 75-year-old Chinese woman with dilated cardiomyopathy and chronic heart failure who experienced abnormal uterine bleeding while taking dapagliflozin. Notably, cessation of dapagliflozin administration resulted in the disappearance of uterine bleeding. These findings suggest that dapagliflozin possesses additional potential mechanisms, but these mechanisms require further investigation. Furthermore, healthcare professionals should remain vigilant regarding the occurrence of uterine bleeding when prescribing dapagliflozin.

Indexed as

Benzhydryl CompoundsCardiomyopathy, DilatedGlucosidesHeart FailureSodium-Glucose Transporter 2 InhibitorsUterine HemorrhageAgedChronic DiseaseFemaleHumansBenzhydryl CompoundsdapagliflozinGlucosidesSodium-Glucose Transporter 2 Inhibitorsabnormal uterine bleedingcardiomyopathycase reportDapagliflozinheart failuremechanismsodium-glucose cotransporter-2 (SGLT2) inhibitor

Identifiers

PMID39180294
PMCPMC11344891

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.