Evidence map›Paper›PMID 39180091›Full record

ArticleJournal of cardiothoracic surgery2024

Early extubation after elective surgical aortic valve replacement during the COVID-19 pandemic.

Anna Fischbach, Julia Alexandra Simons, Steffen B Wiegand, Lieselotte Ammon, Rüdger Kopp, Gernot Marx, Rolf Rossaint, Payam Akhyari, Gereon Schälte

Abstract read
In one paragraph

Article in Journal of cardiothoracic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Anna FischbachDepartment of Anesthesiology, RWTH Aachen University, 52074, Aachen, Germany. afischbach@ukaachen.de.
Julia Alexandra SimonsDepartment of Anesthesiology, RWTH Aachen University, 52074, Aachen, Germany.
Steffen B WiegandDepartment of Anesthesiology and Intensive Care Medicine, Hannover Medical school, 30625, Hannover, Germany.
Lieselotte AmmonDepartment of Anesthesiology, RWTH Aachen University, 52074, Aachen, Germany.
Rüdger KoppDepartment of Intensive Care Medicine, RWTH Aachen University, 52074, Aachen, Germany.
Gernot MarxDepartment of Intensive Care Medicine, RWTH Aachen University, 52074, Aachen, Germany.
Rolf RossaintDepartment of Anesthesiology, RWTH Aachen University, 52074, Aachen, Germany.
Payam AkhyariDepartment of Cardiothoracic Surgery, RWTH Aachen University, 52074, Aachen, Germany.
Gereon SchälteDepartment of Anesthesiology, RWTH Aachen University, 52074, Aachen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSurgical aortic valve replacement (SAVR) is an established therapy for severe calcific aortic stenosis. Enhanced recovery after cardiac surgery (ERACS) protocols have been shown to improve outcomes for elective cardiac procedures. The COVID-19 pandemic prompted early extubation post-elective surgeries to preserve critical care resources. AIM OF THIS STUDY: To investigate the effects of extubating patients within 6 h post-elective SAVR on hospital and ICU length of stay, mortality rates, ICU readmissions, and postoperative pneumonia. STUDY DESIGN AND

methodsThe retrospective analysis at the University Hospital Aachen, Germany, includes data from 2017 to 2022 and compares a total of 73 elective SAVR patients. Among these, 23 patients were extubated within 6 h (EXT group), while 50 patients remained intubated for over 6 h (INT group).

resultsThe INT group experienced longer postoperative ventilation, needed more vasopressor support, had a higher incidence of postoperative pneumonia, and longer ICU length of stay. No significant differences were noted in overall hospital length of stay, mortality, or ICU readmission rates between the groups.

conclusionThis study demonstrates that early extubation in high-risk, multimorbid surgical aortic valve replacement patients is safe, and is associated with a reduction of pneumonia rates, and with shorter ICU and hospital length of stays, reinforcing the benefits of ERACS protocols, especially critical during the COVID-19 pandemic to optimize intensive care use.

Indexed as

Airway ExtubationCOVID-19Elective Surgical ProceduresHeart Valve Prosthesis ImplantationLength of StayAgedAged, 80 and overAortic ValveAortic Valve StenosisFemaleGermanyHumansMaleMiddle AgedPandemicsPostoperative ComplicationsAortic valve surgeryEarly extubationEnhanced recovery after cardiac surgeryERACSSurgical aortic valve replacement

Identifiers

PMID39180091
PMCPMC11344404

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.