Evidence map›Paper›PMID 39180004›Full record

ArticleBMC pulmonary medicine2024

Assessing the impact of triiodothyronine treatment on the lung microbiome of mice with pulmonary fibrosis.

Xiaoshu Guo, Kai Xu, Qiwen Wang, Zongyuan Han, Guoying Yu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pulmonary medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Inter-Organ Communication in Pulmonary Fibrosis: Systemic Modifiers of a Lung-Centered Disease.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xiaoshu GuoState Key Laboratory of Cell Differentiation and Regulation; Henan International Joint Laboratory of Pulmonary Fibrosis; Henan Center for Outstanding Overseas Scientists of Organ Fibrosis; Pingyuan Laboratory; College of Life Science , Henan Normal University, No.46 Jianshe Road, Xinxiang City, 453007, Henan, China. guoxiaoshu@czmc.edu.cn.
Kai XuState Key Laboratory of Cell Differentiation and Regulation; Henan International Joint Laboratory of Pulmonary Fibrosis; Henan Center for Outstanding Overseas Scientists of Organ Fibrosis; Pingyuan Laboratory; College of Life Science , Henan Normal University, No.46 Jianshe Road, Xinxiang City, 453007, Henan, China.
Qiwen WangState Key Laboratory of Cell Differentiation and Regulation; Henan International Joint Laboratory of Pulmonary Fibrosis; Henan Center for Outstanding Overseas Scientists of Organ Fibrosis; Pingyuan Laboratory; College of Life Science , Henan Normal University, No.46 Jianshe Road, Xinxiang City, 453007, Henan, China.
Zongyuan HanState Key Laboratory of Cell Differentiation and Regulation; Henan International Joint Laboratory of Pulmonary Fibrosis; Henan Center for Outstanding Overseas Scientists of Organ Fibrosis; Pingyuan Laboratory; College of Life Science , Henan Normal University, No.46 Jianshe Road, Xinxiang City, 453007, Henan, China.
Guoying YuState Key Laboratory of Cell Differentiation and Regulation; Henan International Joint Laboratory of Pulmonary Fibrosis; Henan Center for Outstanding Overseas Scientists of Organ Fibrosis; Pingyuan Laboratory; College of Life Science , Henan Normal University, No.46 Jianshe Road, Xinxiang City, 453007, Henan, China. guoyingyu@htu.edu.cn.

Funding

Henan Project of Science and Technology 222102310711State Innovation Base for Pulmonary Fibrosis (111 Project), Ministry of Science and Technology, PR China 2019YFE0119500Xinxiang Major Project 21ZD002
6 · The paper itself

Abstract

backgroundIdiopathic pulmonary fibrosis (IPF), an interstitial lung disease, is characterized by the exacerbation of progressive pulmonary fibrosis (PF). IPF primarily affects older individuals and can lead to respiratory failure. This study aimed to assess the effects of triiodothyronine (T

methodsMice were perfused with bleomycin (BLM) to establish a PF model. Using a randomized design, 40 female specific pathogen-free (SPF) C57BL6/N mice were divided into four groups: saline, saline + T

resultsT

conclusionThe administration of T

Indexed as

BleomycinDisease Models, AnimalLungMice, Inbred C57BLMicrobiotaRNA, Ribosomal, 16STriiodothyronineAnimalsFemaleIdiopathic Pulmonary FibrosisMicePulmonary FibrosisBleomycinRNA, Ribosomal, 16STriiodothyronine16S rRNABleomycin (BLM)Idiopathic pulmonary fibrosis (IPF)MicrobiomeMicrobiotaTriiodothyronine

Identifiers

PMID39180004
PMCPMC11344337

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.