Evidence map›Paper›PMID 39179952›Full record

ReviewJournal of thrombosis and thrombolysis2025

The COVID-19 thrombus: distinguishing pathological, mechanistic, and phenotypic features and management.

Richard C Becker, Udaya S Tantry, Muhammad Khan, Paul A Gurbel

Abstract readReview
In one paragraph

Review in Journal of thrombosis and thrombolysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Biomarkers, mechanisms, and precision care in thrombosis.Journal of thrombosis and thrombolysis · 2026
    Article
  2. COVID-19, the disease that changed the world.Medicine and pharmacy reports · 2026
    Review
  3. Post-COVID-19 Jaw Osteonecrosis: A Narrative Review.Medicina (Kaunas, Lithuania) · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Richard C BeckerCardiovascular Center, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, OH, 45267, USA. richard.becker@uc.edu.ORCID http://orcid.org/0000-0002-9878-7707
Udaya S TantrySinai Center for Thrombosis Research and Drug Development, Baltimore, USA.
Muhammad KhanDivision of General Internal Medicine, University of Cincinnati College of Medicine, Cincinnati, USA.
Paul A GurbelSinai Center for Thrombosis Research and Drug Development, Baltimore, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A heightened risk for thrombosis is a hallmark of COVID-19. Expansive clinical experience and medical literature have characterized small (micro) and large (macro) vessel involvement of the venous and arterial circulatory systems. Most events occur in patients with serious or critical illness in the hyperacute (first 1-2 weeks) or acute phases (2-4 weeks) of SARS-CoV-2 infection. However, thrombosis involving the venous, arterial, and microcirculatory systems has been reported in the subacute (4-8 weeks), convalescent (> 8-12 weeks) and chronic phases (> 12 weeks) among patients with mild-to-moderate illness. The purpose of the current focused review is to highlight the distinguishing clinical features, pathological components, and potential mechanisms of venous, arterial, and microvascular thrombosis in patients with COVID-19. The overarching objective is to better understand the proclivity for thrombosis, laying a solid foundation for screening and surveillance modalities, preventive strategies, and optimal patient management.

Indexed as

COVID-19SARS-CoV-2ThrombosisVenous ThrombosisHumansPhenotypeRisk FactorsCOVID-19-associated thrombosisMacrovascular thrombosisMicrovascular thrombosis

Identifiers

PMID39179952
PMCPMC11762605

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.