Evidence map›Paper›PMID 39179915›Full record

Observational studyEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2025

Insights from therapeutic strategies in superior canal dehiscence syndrome: is there anything beyond surgical treatment?

Joan Lorente-Piera, Carlos Prieto-Matos, Nicolás Pérez Fernández, Melissa Blanco-Pareja, Diego Calavia Gil, Manuel Manrique, Raquel Manrique-Huarte

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. [Semicircular canal dehiscence syndrome].Radiologie (Heidelberg, Germany) · 2025
    Review
  2. Review
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joan Lorente-PieraDepartamento de Otorrinolaringología, Clínica Universidad de Navarra, Pamplona, España. jlorentep@unav.es.
Carlos Prieto-MatosDepartamento de Otorrinolaringología, Clínica Universidad de Navarra, Pamplona, España.
Nicolás Pérez FernándezDepartamento de Otorrinolaringología, Clínica Universidad de Navarra, Madrid, España.
Melissa Blanco-ParejaDepartamento de Otorrinolaringología, Clínica Universidad de Navarra, Madrid, España.
Diego Calavia GilDepartamento de Otorrinolaringología, Clínica Universidad de Navarra, Pamplona, España.
Manuel ManriqueDepartamento de Otorrinolaringología, Clínica Universidad de Navarra, Pamplona, España.
Raquel Manrique-HuarteDepartamento de Otorrinolaringología, Clínica Universidad de Navarra, Pamplona, España.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSuperior semicircular canal dehiscence syndrome (SCDS) is a clinical syndrome that can cause instability, vertigo, fullness, tinnitus, autophony, hearing loss (HL), Tullio phenomenon, or Hennebert's sign. Historically, surgery has been the primary treatment reported in the literature, although some medical treatments may also be proposed. This study aims to comprehensively characterize SCDS in a large series of patients from clinical, auditory, and vestibular perspectives, and explore medical alternatives to conventional surgical treatments by comparing their results and evolution.

methodsA retrospective observational study was designed in a tertiary care center. Audiovestibular tests evaluated included pure-tone audiometry (PTA), VEMPs, video head impulse test (vHIT), and CT imaging. Improvement was assessed over a follow-up period of up to 6 months for seven cardinal symptoms to verify the efficacy of the proposed treatments.

results71 subjects with SCDS and a mean age of 51.20 ± 12.22 years were included in the study. The most common symptom found in our sample was instability in 31 patients (43.66%), followed by aural fullness or tinnitus in 29 subjects (40.85%). 36 patients (43.66%) received medical treatment, with 28 of them (77.78%) showing symptom reduction. Surgical repair was indicated in five patients, with all showing symptom improvement. Statistically significant improvement (p < 0.05) was observed, particularly with surgical treatment and acetazolamide, in both symptoms and objective tests such as pure-tone audiometry and VEMPs.

conclusionSCDS shows significant similarities with other otic capsule dehiscences. It is essential to perform VEMPs and CT scans to complete the diagnosis, which is usually accompanied by clearly recognizable clinical criteria. Surgery for SCDS is effective, safe, and without complications. However, in cases where symptoms are mild to moderate, addressing this condition with medical treatment using diuretics such as acetazolamide has shown promising results.

Indexed as

Semicircular Canal DehiscenceSemicircular CanalsAcetazolamideAdultAgedAudiometry, Pure-ToneFemaleHead Impulse TestHumansMaleMiddle AgedRetrospective StudiesTomography, X-Ray ComputedTreatment OutcomeVestibular Evoked Myogenic PotentialsAcetazolamideClinical testCT scanDifferential diagnosisSuperior canal dehiscenceThird window syndromeVEMPVestibular symptoms

Identifiers

PMID39179915

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.